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镁在肌肉完整性和衰老中的整体作用:全面综述。

The Integral Role of Magnesium in Muscle Integrity and Aging: A Comprehensive Review.

机构信息

Kilyos Assessoria, Cursos e Palestras, São Paulo 01311-100, Brazil.

出版信息

Nutrients. 2023 Dec 16;15(24):5127. doi: 10.3390/nu15245127.

DOI:10.3390/nu15245127
PMID:38140385
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10745813/
Abstract

Aging is characterized by significant physiological changes, with the degree of decline varying significantly among individuals. The preservation of intrinsic capacity over the course of an individual's lifespan is fundamental for healthy aging. Locomotion, which entails the capacity for independent movement, is intricately connected with various dimensions of human life, including cognition, vitality, sensory perception, and psychological well-being. Notably, skeletal muscle functions as a pivotal nexus within this intricate framework. Any perturbation in its functionality can manifest as compromised physical performance and an elevated susceptibility to frailty. Magnesium is an essential mineral that plays a central role in approximately 800 biochemical reactions within the human body. Its distinctive physical and chemical attributes render it an indispensable stabilizing factor in the orchestration of diverse cellular reactions and organelle functions, thereby rendering it irreplaceable in processes directly impacting muscle health. This narrative review offers a comprehensive exploration of the pivotal role played by magnesium in maintaining skeletal muscle integrity, emphasizing the critical importance of maintaining optimal magnesium levels for promoting healthy aging.

摘要

衰老是指人体出现显著的生理变化,且不同个体的衰退程度存在较大差异。在个体的生命周期中,保持内在能力是健康衰老的基础。运动能力是独立行动的能力,它与人类生活的各个方面密切相关,包括认知、活力、感官知觉和心理健康。值得注意的是,骨骼肌在这个复杂的框架中起着关键的枢纽作用。其功能的任何干扰都可能表现为身体机能下降和易患脆弱性增加。镁是一种必需的矿物质,在人体内约 800 种生化反应中起着核心作用。其独特的物理和化学属性使其成为协调各种细胞反应和细胞器功能的不可或缺的稳定因素,因此在直接影响肌肉健康的过程中是不可替代的。本综述全面探讨了镁在维持骨骼肌完整性方面的关键作用,强调了维持最佳镁水平对促进健康衰老的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d45e/10745813/e771d2083bc7/nutrients-15-05127-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d45e/10745813/a74e68ce330a/nutrients-15-05127-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d45e/10745813/e771d2083bc7/nutrients-15-05127-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d45e/10745813/a74e68ce330a/nutrients-15-05127-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d45e/10745813/e771d2083bc7/nutrients-15-05127-g002.jpg

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