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比较不同运动训练模式对超重和肥胖成年人全身代谢健康的疗效:一项随机对照试验的网络荟萃分析。

Comparative efficacy of exercise training modes on systemic metabolic health in adults with overweight and obesity: a network meta-analysis of randomized controlled trials.

机构信息

National Clinical Research Center for Metabolic Diseases, Key Laboratory of Diabetes Immunology, Ministry of Education, Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China.

出版信息

Front Endocrinol (Lausanne). 2024 Jan 16;14:1294362. doi: 10.3389/fendo.2023.1294362. eCollection 2023.

DOI:10.3389/fendo.2023.1294362
PMID:38288474
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10823366/
Abstract

OBJECTIVE

This network meta-analysis (NMA) was conducted to compare and rank the effects of training interventions including aerobic exercise (AE), resistance training (RT), combined aerobic and resistance training (CT), and high-intensity interval training (HIIT) on vital metabolic indicators in adults with overweight and obesity.

METHODS

PubMed, Cochrane, Embase, and Web of Science were searched from 1990 to February 2023. Articles were included if they described randomized controlled trials (RCTs) examining the effects of exercise training on anthropometry parameters, lipid profiles, glucose metabolism, blood pressure, and cardiorespiratory fitness in adults with overweight and obesity. Weighted mean difference with 95% CI was calculated.

RESULTS

A total of 28 studies with 1,620 patients were included. Results revealed that AE exerts best effects on weight loss (-2.35 [-4.05, -0.64]) and body mass index (-0.9 [-1.38, -0.42]), while HIIT is the most effective in reducing waist circumference (-5.93 [10.71, -1.15]), percentage body fat (-3.93 [-5.73, -2.12]), serum triglycerides (-20.55 [-37.20, -3.91]), and fasting blood glucose (-14.31 [-22.47, -6.16]) and improving VO max (7.41 [4.37, 10.45]). However, no significant benefit was observed in terms of total cholesterol and blood pressure.

CONCLUSIONS

AE is the optimal exercise type for reducing body weight and BMI, while HIIT exerts the most beneficial effects on improving body composition, cardiorespiratory fitness, and metabolic abnormalities in adults with overweight and obesity.

SYSTEMATIC REVIEW REGISTRATION

https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023444322, identifier CRD42023444322.

摘要

目的

本网络荟萃分析(NMA)旨在比较和评估包括有氧运动(AE)、抗阻训练(RT)、有氧和抗阻联合训练(CT)和高强度间歇训练(HIIT)在内的训练干预措施对超重和肥胖成年人重要代谢指标的影响。

方法

从 1990 年至 2023 年 2 月,检索了 PubMed、Cochrane、Embase 和 Web of Science 数据库。纳入的文章须描述了随机对照试验(RCT),这些试验检查了运动训练对超重和肥胖成年人的人体测量参数、血脂谱、葡萄糖代谢、血压和心肺功能适应性的影响。计算了加权均数差值及其 95%置信区间。

结果

共有 28 项研究纳入了 1620 名患者。结果表明,AE 在体重减轻(-2.35[-4.05,-0.64])和体重指数(-0.9[-1.38,-0.42])方面效果最佳,而 HIIT 在减少腰围(-5.93[10.71,-1.15])、体脂百分比(-3.93[-5.73,-2.12])、血清甘油三酯(-20.55[-37.20,-2.12])、空腹血糖(-14.31[-22.47,-6.16])和提高最大摄氧量(7.41[4.37,10.45])方面最为有效。然而,在总胆固醇和血压方面没有观察到显著的获益。

结论

AE 是减轻体重和 BMI 的最佳运动类型,而 HIIT 对改善超重和肥胖成年人的身体成分、心肺功能适应性和代谢异常最为有益。

系统评价注册

https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023444322,标识符 CRD42023444322。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4420/10823366/157c6b1863fc/fendo-14-1294362-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4420/10823366/aefcf5929b27/fendo-14-1294362-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4420/10823366/157c6b1863fc/fendo-14-1294362-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4420/10823366/aefcf5929b27/fendo-14-1294362-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4420/10823366/157c6b1863fc/fendo-14-1294362-g002.jpg

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