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水凝胶在生物医学中的突破:最新进展及影响。

Hydrogel Breakthroughs in Biomedicine: Recent Advances and Implications.

机构信息

Galgotias College of Pharmacy, Greater Noida, 201310, Uttar Pradesh, India.

Lloyd School of Pharmacy, Knowledge Park II, Greater Noida-201306, Uttar Pradesh, India.

出版信息

Curr Pharm Biotechnol. 2024;25(11):1436-1451. doi: 10.2174/0113892010281021231229100228.

DOI:10.2174/0113892010281021231229100228
PMID:38288792
Abstract

OBJECTIVE

The objective of this review is to present a succinct summary of the latest advancements in the utilization of hydrogels for diverse biomedical applications, with a particular focus on their revolutionary impact in augmenting the delivery of drugs, tissue engineering, along with diagnostic methodologies.

METHODS

Using a meticulous examination of current literary works, this review systematically scrutinizes the nascent patterns in applying hydrogels for biomedical progress, condensing crucial discoveries to offer a comprehensive outlook on their ever-changing importance.

RESULTS

The analysis presents compelling evidence regarding the growing importance of hydrogels in biomedicine. It highlights their potential to significantly enhance drug delivery accuracy, redefine tissue engineering strategies, and advance diagnostic techniques. This substantiates their position as a fundamental element in the progress of modern medicine.

CONCLUSION

In summary, the constantly evolving advancement of hydrogel applications in biomedicine calls for ongoing investigation and resources, given their diverse contributions that can revolutionize therapeutic approaches and diagnostic methods, thereby paving the way for improved patient well-being.

摘要

目的

本综述旨在简洁地总结水凝胶在各种生物医学应用中的最新进展,特别关注其在增强药物输送、组织工程以及诊断方法方面的革命性影响。

方法

通过对当前文献的细致研究,本综述系统地审视了水凝胶在生物医学进展中的新兴应用模式,总结了关键发现,提供了对其不断变化的重要性的全面展望。

结果

分析表明水凝胶在生物医学中的重要性日益增加。它强调了水凝胶在提高药物输送准确性、重新定义组织工程策略和推进诊断技术方面的潜力。这证明了它们作为现代医学进步的基本要素的地位。

结论

总之,鉴于水凝胶在生物医学中的应用不断发展,需要进行持续的研究和资源投入,因为它们的多种贡献可以彻底改变治疗方法和诊断方法,从而改善患者的健康状况。

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An Immunomodulatory Hydrogel by Hyperthermia-Assisted Self-Cascade Glucose Depletion and ROS Scavenging for Diabetic Foot Ulcer Wound Therapeutics.一种通过热疗辅助的自级联葡萄糖耗竭和 ROS 清除的免疫调节水凝胶,用于糖尿病足溃疡伤口治疗。
Adv Mater. 2023 Nov;35(48):e2306632. doi: 10.1002/adma.202306632. Epub 2023 Oct 25.
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Injectable and tissue adhesive EGCG-laden hyaluronic acid hydrogel depot for treating oxidative stress and inflammation.用于治疗氧化应激和炎症的可注射且含表没食子儿茶素没食子酸酯的组织黏附性透明质酸水凝胶储库
Carbohydr Polym. 2023 Jan 1;299:120180. doi: 10.1016/j.carbpol.2022.120180. Epub 2022 Oct 1.
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Polymer Grafting and its chemical reactions.
聚合物接枝及其化学反应。
Front Bioeng Biotechnol. 2023 Jan 11;10:1044927. doi: 10.3389/fbioe.2022.1044927. eCollection 2022.
4
Electrochemical (Bio)Sensing Devices for Human-Microbiome-Related Biomarkers.用于人类微生物组相关生物标志物的电化学(生物)传感设备。
Sensors (Basel). 2023 Jan 11;23(2):837. doi: 10.3390/s23020837.
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Double-Network Hydrogel Films Based on Cellulose Derivatives and κ-Carrageenan with Enhanced Mechanical Strength and Superabsorbent Properties.基于纤维素衍生物和κ-卡拉胶的具有增强机械强度和高吸水性的双网络水凝胶薄膜
Gels. 2022 Dec 27;9(1):20. doi: 10.3390/gels9010020.
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Injectable carboxymethyl chitosan-based hydrogel for simultaneous anti-tumor recurrence and anti-bacterial applications.可注射的羧甲基壳聚糖基水凝胶,用于同时抗肿瘤复发和抗菌应用。
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