Faculty of Pharmacy, Middle East University, Amman, 11831, Jordan.
College of Dentistry, Al-Mustaqbal University, 51001, Babylon, Iraq.
Naunyn Schmiedebergs Arch Pharmacol. 2024 Aug;397(8):5463-5481. doi: 10.1007/s00210-024-03033-7. Epub 2024 Mar 9.
This review paper provides an in-depth analysis of the significance of lipid nanocarriers in drug delivery and the crucial role of characterization techniques. It explores various types of lipid nanocarriers and their applications, emphasizing the importance of microscopy-based characterization methods such as light microscopy, confocal microscopy, transmission electron microscopy (TEM), scanning electron microscopy (SEM), and atomic force microscopy (AFM). The paper also delves into sample preparation, quantitative analysis, challenges, and future directions in the field. The review concludes by underlining the pivotal role of microscopy-based characterization in advancing lipid nanocarrier research and drug delivery technologies.
这篇综述论文深入分析了脂质纳米载体在药物传递中的重要性以及表征技术的关键作用。它探讨了各种类型的脂质纳米载体及其应用，强调了基于显微镜的表征方法的重要性，如光学显微镜、共聚焦显微镜、透射电子显微镜（TEM）、扫描电子显微镜（SEM）和原子力显微镜（AFM）。本文还深入探讨了样品制备、定量分析、挑战以及该领域的未来发展方向。综述最后强调了基于显微镜的表征在推进脂质纳米载体研究和药物传递技术方面的关键作用。
