Ellwood Philippa, Ellwood Eamon, Rutter Charlotte, Perez-Fernandez Virginia, Morales Eva, García-Marcos Luis, Pearce Neil, Asher M Innes, Strachan David
Department of Paediatrics: Child and Youth Health, Faculty of Medical and Health Sciences, University of Auckland, 1023 Auckland, New Zealand.
Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.
J Clin Med. 2020 Nov 17;9(11):3688. doi: 10.3390/jcm9113688.
Background-The Global Asthma Network (GAN) Phase I is surveying school pupils in high-income and low- or middle-income countries using the International Study of Asthma and Allergies in Childhood (ISAAC) methodology. Methods-Cross-sectional surveys of participants in two age groups in randomly selected schools within each centre (2015-2020). The compulsory age group is 13-14 years (adolescents), optionally including parents or guardians. Six to seven years (children) and their parents are also optional. Adolescents completed questionnaires at school, and took home adult questionnaires for parent/guardian completion. Children took home questionnaires for parent/guardian completion about the child and also adult questionnaires. Questions related to symptoms and risk factors for asthma and allergy, asthma management, school/work absence and hospitalisation. Results-53 centres in 20 countries completed quality checks by 31 May 2020. These included 21 centres that previously participated in ISAAC. There were 132,748 adolescents (average response rate 88.8%), 91,802 children (average response rate 79.1%), and 177,622 adults, with >97% answering risk factor questions and >98% answering questions on asthma management, school/work absence and hospitalisation. Conclusion-The high response rates achieved in ISAAC have generally been maintained in GAN. GAN Phase I surveys, partially overlapping with ISAAC centres, will allow within-centre analyses of time-trends in prevalence.
背景——全球哮喘网络（GAN）第一阶段正在使用儿童哮喘和过敏国际研究（ISAAC）方法对高收入国家以及低收入或中等收入国家的在校学生进行调查。方法——在每个中心随机选择的学校中，对两个年龄组的参与者进行横断面调查（2015 - 2020年）。强制年龄组为13 - 14岁（青少年），可选择包括父母或监护人。6至7岁（儿童）及其父母也为可选项。青少年在学校完成问卷，并将成人问卷带回家让父母/监护人填写。儿童将关于孩子的问卷带回家让父母/监护人填写，同时也有成人问卷。问题涉及哮喘和过敏的症状及风险因素、哮喘管理、缺课/缺勤及住院情况。结果——截至2020年5月31日，20个国家的53个中心完成了质量检查。其中包括21个之前参与过ISAAC的中心。有132,748名青少年（平均回复率88.8%）、91,802名儿童（平均回复率79.1%）以及177,622名成年人，超过97%的人回答了风险因素问题，超过98%的人回答了关于哮喘管理、缺课/缺勤及住院情况的问题。结论——ISAAC所取得的高回复率在GAN中总体得以保持。GAN第一阶段的调查与ISAAC中心部分重叠，这将允许对患病率的时间趋势进行中心内分析。
