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用于细胞移植应用的海藻酸盐基水凝胶的最新进展

Recent Advances in Alginate-Based Hydrogels for Cell Transplantation Applications.

作者信息

Kavand Alireza, Noverraz François, Gerber-Lemaire Sandrine

机构信息

Group for Functionalized Biomaterials, Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.

出版信息

Pharmaceutics. 2024 Mar 27;16(4):469. doi: 10.3390/pharmaceutics16040469.

DOI:10.3390/pharmaceutics16040469
PMID:38675129
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11053880/
Abstract

With its exceptional biocompatibility, alginate emerged as a highly promising biomaterial for a large range of applications in regenerative medicine. Whether in the form of microparticles, injectable hydrogels, rigid scaffolds, or bioinks, alginate provides a versatile platform for encapsulating cells and fostering an optimal environment to enhance cell viability. This review aims to highlight recent studies utilizing alginate in diverse formulations for cell transplantation, offering insights into its efficacy in treating various diseases and injuries within the field of regenerative medicine.

摘要

由于其卓越的生物相容性,海藻酸盐成为一种极具前景的生物材料,可用于再生医学的广泛应用。无论是以微粒、可注射水凝胶、刚性支架还是生物墨水的形式,海藻酸盐都为封装细胞和营造促进细胞活力的最佳环境提供了一个多功能平台。本综述旨在突出近期利用不同配方的海藻酸盐进行细胞移植的研究,深入了解其在再生医学领域治疗各种疾病和损伤方面的功效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d496/11053880/db06a0a5ec03/pharmaceutics-16-00469-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d496/11053880/74ef9aab9d0c/pharmaceutics-16-00469-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d496/11053880/2d797f00e96d/pharmaceutics-16-00469-sch001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d496/11053880/30790b804e3c/pharmaceutics-16-00469-sch002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d496/11053880/787bdc4d19a0/pharmaceutics-16-00469-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d496/11053880/b44dbe3bcc11/pharmaceutics-16-00469-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d496/11053880/6f29daab121b/pharmaceutics-16-00469-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d496/11053880/db06a0a5ec03/pharmaceutics-16-00469-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d496/11053880/74ef9aab9d0c/pharmaceutics-16-00469-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d496/11053880/2d797f00e96d/pharmaceutics-16-00469-sch001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d496/11053880/30790b804e3c/pharmaceutics-16-00469-sch002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d496/11053880/787bdc4d19a0/pharmaceutics-16-00469-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d496/11053880/b44dbe3bcc11/pharmaceutics-16-00469-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d496/11053880/6f29daab121b/pharmaceutics-16-00469-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d496/11053880/db06a0a5ec03/pharmaceutics-16-00469-g005.jpg

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