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使用 、 和微流控模型对脑肿瘤进行建模:当前进展综述

Modeling of brain tumors using , and microfluidic models: A review of the current developments.

作者信息

Raju R Richu, AlSawaftah Nour M, Husseini Ghaleb A

机构信息

Biosciences and Bioengineering PhD Program at the American University of Sharjah, Sharjah, United Arab Emirates.

Material Science and Engineering Program at the American University of Sharjah, Sharjah, United Arab Emirates.

出版信息

Heliyon. 2024 May 16;10(10):e31402. doi: 10.1016/j.heliyon.2024.e31402. eCollection 2024 May 30.

Abstract

Brain cancers are some of the most complex diseases to treat, despite the numerous advances science has made in cancer chemotherapy and research. One of the key obstacles to identifying potential cures for this disease is the difficulty in emulating the complexity of the brain and the surrounding microenvironment to understand potential therapeutic approaches. This paper discusses some of the most important , , and microfluidic brain tumor models that aim to address these challenges.

摘要

脑癌是最难治疗的疾病之一,尽管科学在癌症化疗和研究方面取得了诸多进展。识别这种疾病潜在治愈方法的关键障碍之一是难以模拟大脑及其周围微环境的复杂性,以了解潜在的治疗方法。本文讨论了一些旨在应对这些挑战的最重要的、、和微流控脑肿瘤模型。 (注:原文中两个“,,”处信息缺失)

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a948/11130649/2c274e999c22/gr1.jpg

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