酿酒酵母七号染色体遗传图谱的重排。
Rearrangement of the genetic map of chromosome VII of Saccharomyces cerevisiae.
作者信息
Celenza J L, Carlson M
出版信息
Genetics. 1985 Apr;109(4):661-4. doi: 10.1093/genetics/109.4.661.
The genetic map of the right arm of chromosome VII of Saccharomyces cerevisiae includes markers on a distal segment for which meiotic linkage to the centromere-proximal marker cly8 has not previously been demonstrated. According to the currently accepted map, SUF4 is the most distal marker on the right arm. We have shown by tetrad analysis that SUF4 is linked to cly8 and ade6. The genetic distance between SUF4 and cly8 is 29 cM. These data indicate that the genetic map of the right arm of chromosome VII should be revised by inverting the orientation of the distal segment so that SUF4 is located near cly8, and SUC1 and MAL1 are the most distal markers. With this revision, all of the polymeric fermentation markers that have been mapped are located at the ends of chromosomes.
酿酒酵母第七条染色体右臂的遗传图谱包含一个远端区段上的标记，此前尚未证明其与着丝粒近端标记cly8存在减数分裂连锁关系。根据目前公认的图谱，SUF4是右臂上最远端的标记。我们通过四分体分析表明，SUF4与cly8和ade6连锁。SUF4与cly8之间的遗传距离为29厘摩。这些数据表明，第七条染色体右臂的遗传图谱应通过反转远端区段的方向进行修订，使SUF4位于cly8附近，而SUC1和MAL1是最远端的标记。通过这次修订，所有已定位的聚合发酵标记都位于染色体末端。
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