Simchen G, Chapman K B, Caputo E, Nam K, Riles L, Levin D E, Boeke J D
Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.
Genetics. 1994 Oct;138(2):283-7. doi: 10.1093/genetics/138.2.283.
The Saccharomyces cerevisiae dbr1 mutation has been mapped on the left arm of chromosome XI. XIL is a chromosome arm that was until now rather sparsely populated with accurately mapped markers. On the basis of physical data, the overall order of markers is inverted relative to the existing genetic map of XI. We present tetrad analyses using a variety of markers on XI that indicate that the existing genetic map of XIL should be inverted, at least for the strains in which our mapping was carried out, and probably for other S. cerevisiae strains.
酿酒酵母dbr1突变已被定位在第十一条染色体的左臂上。XIL是一条染色体臂，到目前为止其上精确映射的标记相对较少。根据物理数据，标记的总体顺序相对于第十一条染色体现有的遗传图谱是颠倒的。我们使用第十一条染色体上的多种标记进行了四分体分析，结果表明XIL现有的遗传图谱应该颠倒过来，至少对于我们进行图谱绘制的菌株是这样，可能对于其他酿酒酵母菌株也是如此。
