Liu Jianying, Zhang Binzhi, Wang Leqi, Li Shasha, Long Qinqiang, Xiao Xue
Guangdong Metabolic Diseases Research Center of Integrated Chinese and Western Medicine (Institute of Chinese Medicine), Guangdong Pharmaceutical University, Guangzhou 510006, China.
The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou Higher Education Mega Center, Guangzhou 510120, China.
Chin Herb Med. 2024 Jan 17;16(3):375-391. doi: 10.1016/j.chmed.2023.09.007. eCollection 2024 Jul.
is a Chinese medicinal fungus with a long history of use in healthcare and disease treatment. spores (GLS) are tiny germ cells released from the mushroom cap during the mature stage of growth. They contain all the genetic active substances of . spore oil (GLSO) is a lipid component extracted from broken-walled spores using supercritical CO extraction technology. GLSO contains fatty acids, triterpenes, sterols and other bioactive compounds. Previous studies have demonstrated that GLSO has a wide range of pharmacological properties, including anti-tumor, anti-aging, neuroprotection, immunomodulation, hepatoprotection and modulation of metabolic diseases. This review summarizes the research progress of GLSO over the past two decades in terms of its bioactive components, extraction and processing techniques, pharmacological effects and safety evaluation. This provides a solid foundation for further research and application of GLSO.
是一种在医疗保健和疾病治疗方面有着悠久使用历史的中药材。孢子（GLS）是在生长成熟阶段从蘑菇菌盖释放出的微小生殖细胞。它们含有[该药材名称]的所有遗传活性物质。孢子油（GLSO）是采用超临界CO萃取技术从破壁[该药材名称]孢子中提取的脂质成分。GLSO含有脂肪酸、三萜类化合物、甾醇和其他生物活性化合物。先前的研究表明，GLSO具有广泛的药理特性，包括抗肿瘤、抗衰老、神经保护、免疫调节、肝脏保护以及对代谢性疾病的调节作用。本综述总结了过去二十年中GLSO在其生物活性成分、提取和加工技术、药理作用及安全性评价方面的研究进展。这为GLSO的进一步研究和应用提供了坚实的基础。
