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2023 年埃及野生鼠携带的高致病性禽流感病毒 H5N1 属 2.3.4.4b 分支。

Highly pathogenic avian influenza virus H5N1 clade 2.3.4.4b in wild rats in Egypt during 2023.

机构信息

Centre of Scientific Excellence for Influenza Viruses, National Research Centre, Giza, Egypt.

Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN, USA.

出版信息

Emerg Microbes Infect. 2024 Dec;13(1):2396874. doi: 10.1080/22221751.2024.2396874. Epub 2024 Aug 30.

DOI:10.1080/22221751.2024.2396874
PMID:39193629
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11382695/
Abstract

We detected highly pathogenic avian influenza A(H5N1) virus in wild rats collected from a rural area in Giza, Egypt, near poultry farms, markets, and backyard flocks. Sequence and phylogenetic analyses indicated that the virus from the rats belonged to clade 2.3.4.4b, which has been the predominant virus genotype circulating in Egypt and worldwide since 2021-2022. Active surveillance of avian influenza viruses in wild and domestic mammals is recommended to prevent further spread to mammals and humans.

摘要

我们在埃及吉萨的一个农村地区、家禽养殖场、市场和后院禽群附近采集的野生鼠类中检测到了高致病性禽流感病毒 A(H5N1)。序列和系统发育分析表明，这些来自老鼠的病毒属于 2.3.4.4b 分支，自 2021-2022 年以来，该分支一直是埃及和全球流行的主要病毒基因型。建议对野生动物和家养哺乳动物中的流感病毒进行主动监测，以防止进一步传播给哺乳动物和人类。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e896/11382695/6f6340d9b38f/TEMI_A_2396874_F0001b_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e896/11382695/de7262b17720/TEMI_A_2396874_F0001a_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e896/11382695/6f6340d9b38f/TEMI_A_2396874_F0001b_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e896/11382695/de7262b17720/TEMI_A_2396874_F0001a_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e896/11382695/6f6340d9b38f/TEMI_A_2396874_F0001b_OC.jpg

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