Xi'an Key Laboratory of Stem Cell and Regenerative Medicine, Institute of Medical Research, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an 710072, China.
Research & Development Institute, Northwestern Polytechnical University in Shenzhen, 45 South Gaoxin Road, Shenzhen 518057, China.
Biosensors (Basel). 2024 Jul 29;14(8):369. doi: 10.3390/bios14080369.
As a commonly used metal ion, iron(II) (Fe) ions pose a potential threat to ecosystems and human health. Therefore, it is particularly important to develop analytical techniques for the rapid and accurate detection of Fe ions. However, the development of near-infrared (NIR) luminescence probes with good photostability for Fe ions remain challenging. In this work, we report a novel iridium(III) complex-based luminescence probe for the sensitive and rapid detection of Fe ions in a solution based on an Fe-mediated reduction reaction. This probe is capable of sensitively detecting Fe ions with a limit of detection (LOD) of 0.26 μM. Furthermore, this probe shows high photostability, and its luminescence remains stable under 365 nm irradiation over a time period of 30 min. To our knowledge, this is first iridium(III) complex-based NIR probe for the detection of Fe ions. We believe that this work provides a new method for the detection of Fe ions and has great potential for future applications in water quality testing and human monitoring.
作为一种常用的金属离子，二价铁（Fe）离子对生态系统和人类健康构成潜在威胁。因此，开发用于快速、准确检测 Fe 离子的分析技术尤为重要。然而，开发具有良好光稳定性的近红外（NIR）发光探针用于 Fe 离子仍然具有挑战性。在这项工作中，我们报告了一种基于铱（III）配合物的新型荧光探针，用于基于 Fe 介导的还原反应灵敏快速地检测溶液中的 Fe 离子。该探针能够灵敏地检测 Fe 离子，其检测限（LOD）为 0.26 μM。此外，该探针具有高的光稳定性，在 365nm 照射下，其发光在 30 分钟内保持稳定。据我们所知，这是首例用于检测 Fe 离子的基于铱（III）配合物的近红外探针。我们相信，这项工作为 Fe 离子的检测提供了一种新方法，在水质检测和人体监测等领域具有广阔的应用前景。
