Rezakhani Leila, Gharibshahian Maliheh, Salehi Majid, Zamani Sepehr, Abpeikar Zahra, Ghaderzadeh Omid, Alizadeh Morteza, Masoudi Alireza, Rezaei Nariman, Cheraghali Danial
Fertility and Infertility Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Department of Tissue Engineering, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Regen Ther. 2024 Aug 28;26:635-645. doi: 10.1016/j.reth.2024.08.015. eCollection 2024 Jun.
Hydrogels are biomolecules made of artificial and natural polymers. Their quasi-three-dimensional structure has created unique features. They are very hydrophilic, and in addition to the high inflation rate, they also have excellent water maintenance capacity, biodegradability, biocompatibility, and strong mechanical properties. These properties are used in many tissue engineering applications. All these features have made these scaffolds widely used as attractive structures in the world of tissue engineering and regeneration medicine. In addition to research, scaffolds entered the field of medicine and are expected to play a significant role in the repair of many tissues in the future. This study aims to review the various polymers involved in hydrogel fabrication and their application in the repair of diverse tissues and clinical trials.
水凝胶是由人工和天然聚合物制成的生物分子。它们的准三维结构具有独特的特性。它们具有很强的亲水性，除了高膨胀率外，还具有出色的保水能力、生物降解性、生物相容性和强大的机械性能。这些特性被应用于许多组织工程应用中。所有这些特性使这些支架在组织工程和再生医学领域中作为有吸引力的结构被广泛使用。除了研究之外，支架已进入医学领域，并有望在未来许多组织的修复中发挥重要作用。本研究旨在综述参与水凝胶制备的各种聚合物及其在不同组织修复和临床试验中的应用。
