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Location of the c-yes gene on the human chromosome and its expression in various tissues.

作者信息

Semba K, Yamanashi Y, Nishizawa M, Sukegawa J, Yoshida M, Sasaki M, Yamamoto T, Toyoshima K

出版信息

Science. 1985 Mar 1;227(4690):1038-40. doi: 10.1126/science.2983418.

DOI:10.1126/science.2983418
PMID:2983418
Abstract

Analysis of DNA from human embryo fibroblasts showed that ten Eco RI fragments were hybridizable with the Yamaguchi sarcoma virus oncogene (v-yes). Four of the Eco RI fragments were assigned to chromosome 18 and one to chromosome 6. There was evidence for multiple copies of yes-related genes in the human genome; however, only a single RNA species, 4.8 kilobases in length, was related to yes in various cells.

摘要

相似文献

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Location of the c-yes gene on the human chromosome and its expression in various tissues.
Science. 1985 Mar 1;227(4690):1038-40. doi: 10.1126/science.2983418.
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Identification of a human gene (HCK) that encodes a protein-tyrosine kinase and is expressed in hemopoietic cells.鉴定出一种编码蛋白酪氨酸激酶且在造血细胞中表达的人类基因(HCK)。
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Cellular proteins homologous to the viral yes gene product.与病毒yes基因产物同源的细胞蛋白。
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