肉桂、迷迭香和牛至对感染空肠弯曲杆菌肉鸡生长性能、血液生化指标、肝酶活性、粪便微生物群和回肠形态的影响。

Effects of cinnamon, rosemary and oregano on growth performance, blood biochemistry, liver enzyme activities, excreta microbiota and ileal morphology of Campylobacter jejuni-challenged broiler chickens.

机构信息

Department of Animal Science, Faculty of Agriculture, Ilam University, Ilam, Iran.

Department of Animal Science, Faculty of Agriculture and Natural Resources, Persian Gulf University, Bushehr, Iran.

出版信息

Vet Med Sci. 2024 Nov;10(6):e70034. doi: 10.1002/vms3.70034.

DOI:10.1002/vms3.70034

PMID:39294894

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11410678/

Abstract

BACKGROUND

Phytogenic additives would be helpful to mitigate the detrimental impact of Campylobacter jejuni on broiler chickens.

OBJECTIVE

The experiment aimed to assess the effects of cinnamon, rosemary and oregano powder on physiological responses of broiler chickens challenged with C. jejuni from 0 to 42 days of age.

METHODS

A total of 192 one-day-old male broiler chickens were divided into 6 treatment groups. The treatments included: negative control (NC; basal diet without additives and no C. jejuni challenge), positive control (PC; basal diet with C. jejuni challenge), PC with cinnamon, rosemary or oregano powder (3 g/kg each), and PC with Erythromycin (55 mg/kg). Except for the NC group, all chicks were orally challenged with 2 × 10 CFU/mL C. jejuni daily from days 21-25. Feed intake, body weight gain (BWG), feed conversion ratio (FCR), energy efficiency ratio (EER) and protein efficiency ratio (PER) were assessed during the rearing period (0-42 days). On day 42 of age, fresh excreta samples were collected from each pen to determine apparent dry matter digestibility and excreta microbiota. In addition, at the end of the experiment, blood samples were collected to evaluate blood profile and liver enzyme activities.

RESULTS

C. jejuni challenge (PC treatment) decreased BWG, EER and PER, while increasing FCR of broiler chickens (p < 0.05), whereas rosemary, oregano and Erythromycin improved these performance parameters akin to NC. PC diet showed negative effect in ileal morphology, alleviated by additives except cinnamon (p < 0.05). Dietary additives successfully reduced Campylobacter levels and increased Lactobacilli counts in the PC. Rosemary and oregano lowered plasma total cholesterol (p < 0.05). Alanine aminotransferase elevation by C. jejuni challenge in the PC group was prevented by rosemary, oregano and Erythromycin (p < 0.05).

CONCLUSIONS

Oregano and rosemary alleviate the impact of C. jejuni challenge.

摘要

背景

植物源添加剂有助于减轻空肠弯曲杆菌对肉鸡的不利影响。

目的

本试验旨在评估肉桂、迷迭香和牛至粉对 0~42 日龄感染空肠弯曲杆菌肉鸡的生理反应的影响。

方法

将 192 只 1 日龄雄性肉鸡分为 6 个处理组。处理组包括：阴性对照（NC；基础日粮，无添加剂，无空肠弯曲杆菌攻毒）、阳性对照（PC；基础日粮，有空肠弯曲杆菌攻毒）、肉桂、迷迭香或牛至粉（各 3 g/kg）和 PC 加红霉素（55 mg/kg）。除 NC 组外，所有雏鸡于 21~~25 日龄每天经口感染 2×10 CFU/mL 空肠弯曲杆菌。在育雏期（0~~42 日龄）评估采食量、体重增重（BWG）、饲料转化率（FCR）、能量效率比（EER）和蛋白质效率比（PER）。42 日龄时，从每个鸡舍收集新鲜粪便样本来测定表观干物质消化率和粪便微生物群。此外，在试验结束时，采集血液样本以评估血液指标和肝脏酶活性。

结果

空肠弯曲杆菌攻毒（PC 处理）降低了肉鸡的 BWG、EER 和 PER，而增加了 FCR（p<0.05），而迷迭香、牛至和红霉素改善了这些性能参数，类似于 NC。PC 日粮对回肠形态有负面影响，除肉桂外，添加剂均可缓解（p<0.05）。日粮添加剂成功降低了 PC 中的空肠弯曲杆菌水平和增加了乳酸杆菌数量。迷迭香和牛至降低了血浆总胆固醇（p<0.05）。空肠弯曲杆菌攻毒引起的丙氨酸氨基转移酶升高被迷迭香、牛至和红霉素所预防（p<0.05）。