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饮酒与心血管疾病:对不断演变的观点及长期影响的叙述性综述

Alcohol Consumption and Cardiovascular Disease: A Narrative Review of Evolving Perspectives and Long-Term Implications.

作者信息

Georgescu Ovidiu Stefan, Martin Liviu, Târtea Georgică Costinel, Rotaru-Zavaleanu Alexandra-Daniela, Dinescu Sorin Nicolae, Vasile Ramona Constantina, Gresita Andrei, Gheorman Veronica, Aldea Madalina, Dinescu Venera Cristina

机构信息

Doctoral School, University of Medicine and Pharmacy of Craiova, 2 Petru Rares Str., 200349 Craiova, Romania.

Faculty of Medical Care, Titu Maiorescu University, Văcărești Road, no 187, 040051 Bucharest, Romania.

出版信息

Life (Basel). 2024 Sep 9;14(9):1134. doi: 10.3390/life14091134.

DOI:10.3390/life14091134
PMID:39337917
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11433171/
Abstract

Cardiovascular illnesses remain the primary cause of death, accounting for at least 17.9 million fatalities per year and posing a significant public health problem because of its extensive predominance and effect on healthcare systems. The etiology of cardiovascular disease is complex and involves several environmental and lifestyle factors. Alcohol use is a highly important determinant because of its dual-edged effect on cardiovascular health. Multiple studies indicate that moderate alcohol consumption may have certain advantages, such as slight enhancements in lipid profiles. Conversely, excessive alcohol intake is associated with serious negative consequences, including cardiomyopathy, hypertension, arrhythmias, and even mortality. The aim of this study is to provide a comprehensive analysis of the several effects of alcohol on cardiovascular health and their understanding within the medical field over time. It uses an interpretative narrative review methodology and analyzes studies that focus on genetic risk factors, gender differences, and shifts in paradigms in recent years. This article highlights the need for obtaining a thorough understanding of the effects of alcohol on cardiovascular health to support public health guidelines and clinical practice, and it underscores the significance of including alcohol consumption into the broader context of cardiovascular risk management and identifies important subjects for further study.

摘要

心血管疾病仍然是主要的死亡原因,每年至少造成1790万人死亡,因其广泛的普遍性和对医疗系统的影响而构成重大的公共卫生问题。心血管疾病的病因复杂,涉及多种环境和生活方式因素。饮酒是一个非常重要的决定因素,因为它对心血管健康具有双刃剑效应。多项研究表明,适度饮酒可能有某些益处,比如对血脂水平有轻微改善。相反,过量饮酒会带来严重的负面后果,包括心肌病、高血压、心律失常,甚至死亡。本研究的目的是全面分析饮酒对心血管健康的多种影响以及随着时间推移医学界对这些影响的认识。它采用解释性叙述综述方法,分析关注遗传风险因素、性别差异以及近年来范式转变的研究。本文强调需要全面了解饮酒对心血管健康的影响,以支持公共卫生指南和临床实践,并强调将饮酒纳入更广泛的心血管风险管理背景的重要性,同时确定进一步研究的重要课题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96ae/11433171/ca4c1c81d80c/life-14-01134-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96ae/11433171/e1edb1fcf26e/life-14-01134-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96ae/11433171/ca4c1c81d80c/life-14-01134-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96ae/11433171/e1edb1fcf26e/life-14-01134-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96ae/11433171/ca4c1c81d80c/life-14-01134-g002.jpg

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