Kaifi Reham
Department of Radiological Sciences, College of Applied Medical Sciences, King Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia.
King Abdullah International Medical Research Center, Jeddah, Saudi Arabia.
Front Oncol. 2024 Sep 20;14:1437185. doi: 10.3389/fonc.2024.1437185. eCollection 2024.
Brain tumors are characterized by abnormal cell growth within or around the brain, posing severe health risks often associated with high mortality rates. Various imaging techniques, including magnetic resonance imaging (MRI), are commonly employed to visualize the brain and identify malignant growths. Computer-aided diagnosis tools (CAD) utilizing Convolutional Neural Networks (CNNs) have proven effective in feature extraction and predictive analysis across diverse medical imaging modalities.
This study explores a CNN trained and evaluated with nine activation functions, encompassing eight established ones from the literature and a modified version of the soft sign activation function.
The latter demonstrates notable efficacy in discriminating between four types of brain tumors in MR images, achieving an accuracy of 97.6%. The sensitivity for glioma is 93.7%; for meningioma, it is 97.4%; for cases with no tumor, it is 98.8%; and for pituitary tumors, it reaches 100%.
In this manuscript, we propose an advanced CNN architecture that integrates a newly developed activation function. Our extensive experimentation and analysis showcase the model's remarkable ability to precisely distinguish between different types of brain tumors within a substantial and diverse dataset. The findings from our study suggest that this model could serve as an invaluable supplementary tool for healthcare practitioners, including specialized medical professionals and resident physicians, in the accurate diagnosis of brain tumors.
脑肿瘤的特征是大脑内部或周围的细胞异常生长,常带来严重的健康风险,死亡率往往很高。包括磁共振成像(MRI)在内的各种成像技术通常用于可视化大脑并识别恶性肿瘤生长。利用卷积神经网络(CNN)的计算机辅助诊断工具(CAD)已被证明在各种医学成像模态的特征提取和预测分析中有效。
本研究探索了一种用九种激活函数训练和评估的CNN,其中包括文献中已有的八种以及软符号激活函数的一个修改版本。
后者在区分磁共振图像中的四种脑肿瘤类型方面显示出显著效果,准确率达到97.6%。对胶质瘤的敏感性为93.7%;对脑膜瘤为97.4%;对无肿瘤病例为98.8%;对垂体瘤则达到100%。
在本论文中,我们提出了一种集成新开发激活函数的先进CNN架构。我们广泛的实验和分析展示了该模型在一个庞大且多样的数据集中精确区分不同类型脑肿瘤的卓越能力。我们研究的结果表明,该模型可以作为医疗从业者(包括专业医学专家和住院医师)在脑肿瘤准确诊断中的宝贵辅助工具。