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BCCHI-HCNN:使用混合深度卷积神经网络模型从组织病理学图像进行乳腺癌分类

BCCHI-HCNN: Breast Cancer Classification from Histopathological Images Using Hybrid Deep CNN Models.

作者信息

Pandey Saroj Kumar, Rathore Yogesh Kumar, Ojha Manoj Kumar, Janghel Rekh Ram, Sinha Anurag, Kumar Ankit

机构信息

Department of Computer Engineering & Applications, GLA University, Mathura, India.

Department of Computer Science & Engineering, Shri Shankaracharya Institute of Professional Management and Technology, Raipur, India.

出版信息

J Imaging Inform Med. 2025 Jun;38(3):1690-1703. doi: 10.1007/s10278-024-01297-2. Epub 2024 Oct 14.

Abstract

Breast cancer is the most common cancer in women globally, imposing a significant burden on global public health due to high death rates. Data from the World Health Organization show an alarming annual incidence of nearly 2.3 million new cases, drawing the attention of patients, healthcare professionals, and governments alike. Through the examination of histopathological pictures, this study aims to revolutionize the early and precise identification of breast cancer by utilizing the capabilities of a deep convolutional neural network (CNN)-based model. The model's performance is improved by including numerous classifiers, including support vector machine (SVM), decision tree, and K-nearest neighbors (KNN), using transfer learning techniques. The studies include evaluating two separate feature vectors, one with and one without principal component analysis (PCA). Extensive comparisons are made to measure the model's performance against current deep learning models, including critical metrics such as false positive rate, true positive rate, accuracy, precision, and recall. The data show that the SVM algorithm with PCA features achieves excellent speed and accuracy, with an amazing accuracy of 99.5%. Furthermore, although being somewhat slower than SVM, the decision tree model has the greatest accuracy of 99.4% without PCA. This study suggests a viable strategy for improving early breast cancer diagnosis, opening the path for more effective healthcare treatments and better patient outcomes.

摘要

乳腺癌是全球女性中最常见的癌症,因其高死亡率给全球公共卫生带来了沉重负担。世界卫生组织的数据显示,每年新增病例近230万,这一惊人的发病率引起了患者、医疗专业人员和政府的关注。通过对组织病理学图片的检查,本研究旨在利用基于深度卷积神经网络(CNN)的模型的能力,彻底改变乳腺癌的早期精确识别。通过使用迁移学习技术,包括支持向量机(SVM)、决策树和K近邻(KNN)等众多分类器,提高了该模型的性能。这些研究包括评估两个单独的特征向量,一个有主成分分析(PCA),一个没有主成分分析。进行了广泛的比较,以衡量该模型相对于当前深度学习模型的性能,包括误报率、真阳性率、准确率、精确率和召回率等关键指标。数据显示,具有PCA特征的SVM算法具有出色的速度和准确率,惊人地达到了99.5%。此外,虽然决策树模型比SVM稍慢,但在没有PCA的情况下,其准确率最高,为99.4%。本研究提出了一种改进早期乳腺癌诊断的可行策略,为更有效的医疗治疗和更好的患者预后开辟了道路。

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本文引用的文献

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Artificial intelligence in the interpretation of breast cancer on MRI.人工智能在乳腺磁共振成像中对乳腺癌的解读
J Magn Reson Imaging. 2020 May;51(5):1310-1324. doi: 10.1002/jmri.26878. Epub 2019 Jul 25.
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BACH: Grand challenge on breast cancer histology images.BACH:乳腺癌组织学图像的重大挑战。
Med Image Anal. 2019 Aug;56:122-139. doi: 10.1016/j.media.2019.05.010. Epub 2019 May 31.

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