Peimani Maryam, Esfahani Zahra, Bandarian Fatemeh, Esmaeili Shahnaz, Moghaddam Sahar Saeedi, Namazi Nazli, Koolaji Sogol, Stewart Anita L, Ebrahimi Narges, Rezaei Negar, Rezaei Nazila, Farzadfar Farshad, Nasli-Esfahani Ensieh, Larijani Bagher
Diabetes Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Iran J Public Health. 2024 Apr;53(4):913-923. doi: 10.18502/ijph.v53i4.15569.
This study presents estimates for type 2 diabetes mellitus (T2DM) burden and attributable risk factors in Iran from 1990-2019, using data from the 2019 Global Burden of Disease study.
This study reports prevalence, incidence, death, disability-adjusted life years (DALYs), years of life lost (YLLs), and years lived with disability (YLDs) of T2DM in Iran, by sex, age, and province, from 1990 to 2019. We also present the T2DM burden attributable to risk factors. Results are reported in absolute number and age-standardized rates.
Overall, the burden of T2DM had increased greatly since 1990. In 2019, the T2DM incidence and prevalence cases were 291,482 (a 374% increase) and 5,035,012 (a 417% increase) respectively. Moreover, the number of death and DALYs were 14,191 (a 488% increase) and 716,457 (a 417% increase) respectively. DALYs and YLDs in women were consistently higher than men were, whereas women experienced slower increases in YLLs from 1990 to 2019. The age-standardized DALYs rate increased for all Iranian provinces during study period. High body-mass index, ambient particulate matter pollution, and low physical activity remained the three major attributable risk factors in all provinces in 2019.
T2DM constitutes a major health burden in Iran. The remarkable upsurge in the T2DM burden represents an ongoing challenge, given the rapidly aging population in Iran. Thus, integrated and multi-sectoral actions that decrease exposure to risk factors and improve the prevention and early diagnosis are needed.
本研究利用2019年全球疾病负担研究的数据，呈现了1990年至2019年伊朗2型糖尿病（T2DM）的负担及可归因风险因素的估计情况。
本研究报告了1990年至2019年伊朗按性别、年龄和省份划分的T2DM的患病率、发病率、死亡率、伤残调整生命年（DALYs）、寿命损失年数（YLLs）和伤残生存年数（YLDs）。我们还展示了可归因于风险因素的T2DM负担。结果以绝对数和年龄标准化率报告。
总体而言，自1990年以来T2DM的负担大幅增加。2019年，T2DM的发病率和患病率分别为291,482例（增加了374%）和5,035,012例（增加了417%）。此外，死亡人数和DALYs分别为14,191例（增加了488%）和716,457例（增加了417%）。女性的DALYs和YLDs一直高于男性，而从1990年到至2019年女性的YLLs增长较慢。在研究期间，伊朗所有省份的年龄标准化DALYs率均有所上升。2019年，高体重指数、环境颗粒物污染和低体力活动仍然是所有省份的三大主要可归因风险因素。
T2DM是伊朗的一项重大健康负担。鉴于伊朗人口迅速老龄化，T2DM负担的显著激增是一项持续的挑战。因此，需要采取综合的多部门行动，以减少接触风险因素，并改善预防和早期诊断。
