Velluto Calogero, Mundis Gregory, Scaramuzzo Laura, Perna Andrea, Capece Giacomo, Cruciani Andrea, Inverso Michele, Borruto Maria Ilaria, Proietti Luca
Catholic University of the Sacred Heart, Rome, Italy.
Department of Aging, Orthopaedic and Rheumatological Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Front Surg. 2024 Oct 15;11:1446792. doi: 10.3389/fsurg.2024.1446792. eCollection 2024.
The assessment of segmental fusion after Lateral Lumbar Interbody fusion (LLIF) using 3D-printed porous titanium cage is still not well studied. Various criteria, such as the presence of bone bridges (BB) between adjacent vertebrae, serve as indicators for anterior fusion. However, limited radiological studies have investigated zygapophyseal joints (ZJ) status following LLIF with porous titanium cages vs. conventional titanium threaded cages. The porous design of the latest titanium intervertebral cages is thought to enhance the bone-to-implant fusion rate. This radiological study aimed to compare the fusion patterns post-LLIF using 3D-printed porous titanium cages against those using threaded titanium cages. This radiological study aimed to compare the fusion patterns after LLIF using 3D-printed porous titanium cages against those using threaded titanium cages.
This retrospective, single-center radiological study involved 135 patients who underwent LLIF and posterior percutaneous screw fixation for degenerative spondylolisthesis. The study included 51 patients (Group A) with the novel porous titanium cages and 84 patients (Group B) with conventional threaded titanium cages. Inclusion criteria mandated complete radiological data and a minimum follow-up period of 24 months. The study evaluated intervertebral bone bridges (BB) for anterior fusion and zygapophyseal joints (ZJ) ankylotic degeneration, based on Pathria et al., as evidence of posterior fusion and segmental immobilization.
Two years after surgery, intervertebral BB were identified in 83 segments (94.31%) in Group A and in 87 segments (88.77%) in Group B. ZJ Pathria grade I was observed in 2 segments (2.27%) of Group A and in 4 segments (4.08%) of Group B. Grade II was seen in 5 segments (5.68%) of Group A and in 6 segments (6.12%) of Group B. Posterior fusion, classified as grade III, was found in 81 segments (92.04%) of Group A and 88 segments (89.79%) of Group B. Subsidence incidence was 5.88% (3 segments) for the novel cage and 9.88% (8 segments) for the conventional cage.
The architecture of porous titanium cages offers a promising solution for increasing bone ingrowth and bridging space, supporting successful spinal fusion while minimizing the risk of subsidence.
使用3D打印多孔钛笼进行腰椎侧方椎间融合术(LLIF)后节段融合的评估仍未得到充分研究。各种标准,如相邻椎体之间骨桥(BB)的存在,可作为前路融合的指标。然而,有限的放射学研究调查了使用多孔钛笼与传统钛螺纹笼进行LLIF后关节突关节(ZJ)的状态。最新款钛椎间融合器的多孔设计被认为可提高骨与植入物的融合率。这项放射学研究旨在比较使用3D打印多孔钛笼与使用螺纹钛笼进行LLIF后的融合模式。
这项回顾性单中心放射学研究纳入了135例行LLIF及后路经皮螺钉固定治疗退行性腰椎滑脱的患者。研究包括51例使用新型多孔钛笼的患者(A组)和84例使用传统螺纹钛笼的患者(B组)。纳入标准要求有完整的放射学数据且最短随访期为24个月。该研究根据Pathria等人的方法评估椎间骨桥(BB)以判断前路融合情况,以及关节突关节(ZJ)的强直性退变情况,作为后路融合和节段固定的证据。
术后两年,A组83个节段(94.31%)发现椎间BB,B组87个节段(88.77%)发现椎间BB。A组2个节段(2.27%)观察到ZJ Pathria I级,B组4个节段(4.08%)观察到ZJ Pathria I级。A组5个节段(5.68%)观察到II级,B组6个节段(6.12%)观察到II级。后路融合,分类为III级,在A组81个节段(92.04%)和B组88个节段(89.79%)中发现。新型融合器的下沉发生率为5.88%(3个节段),传统融合器的下沉发生率为9.88%(8个节段)。
多孔钛笼的结构为增加骨长入和桥接间隙提供了一个有前景的解决方案,有助于成功的脊柱融合,同时将下沉风险降至最低。