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用于蛋白质识别和痕量检测的波长复用红外超表面

Wavelength multiplexing infrared metasurfaces for protein recognition and trace detection.

作者信息

Dong Shiqing, Dong Chao, Shen Kesheng, Zheng Yun, Sun Jie, Zhen Cheng, Hu Haiyang, Zhang Feng, Zhang Zhe, Liu Hongchao, Lu Hai

机构信息

Engineering Laboratory for Optoelectronic Technology and Advanced Manufacturing, School of Physics, Henan Normal University, Xinxiang 453007, China.

Henan Key Laboratory of Optoelectronic Sensing Integrated Application, College of Electronic and Electrical Engineering, Henan Normal University, Xinxiang 453007, China.

出版信息

Nanophotonics. 2023 Sep 26;12(20):3963-3976. doi: 10.1515/nanoph-2023-0517. eCollection 2023 Oct.

Abstract

Infrared metasurfaces have exhibited exceptional optical properties that differ from naturally occurring metallic and dielectric nanostructure, enabling non-destructive and label-free sensing in a broadband region. However, implementing wavelength multiplexing sensors in broadband infrared has faced significant challenges. These challenges arise from the difficulty in efficiently exciting high resonances at specific wavelengths and the inability to individually tune each resonance. Herein, we present a dual resonant metasurface that utilizes a metal-dielectric-metal plasmonic grating and a dielectric-metal channel. By adjusting the vertical and horizontal structures of metasurface, we can independently modify the spectrum of the metasurface in the near-infrared and mid-infrared regions. This broadband infrared metasurface exhibits robust spectral regulation, enabling a polarization-dependent strategy for the dual-resonance. It offers a competitive advantage over traditional metallic nanostructure in refractive index sensing at the second near-infrared window and ultrasensitive vibrational spectroscopy in mid-infrared. Specifically, our proposed metasurface achieves protein concentration sensing and dynamic monitoring of protein concentration in the infrared two-zone. Additionally, it enhances the mid-infrared absorption of amide II with a high resonance. The metasurface which combines wavelength multiplexing and polarization dependent switch for protein recognition and trace detection, presents a novel approach for developing high-performance sensors and Integrated photonics sensors in the broadband infrared region.

摘要

红外超表面展现出了与天然存在的金属和介电纳米结构不同的卓越光学特性,能够在宽带区域实现无损且无标记的传感。然而,在宽带红外中实现波长复用传感器面临着重大挑战。这些挑战源于难以在特定波长高效激发高共振以及无法单独调谐每个共振。在此,我们展示了一种双共振超表面,它利用了金属 - 介质 - 金属等离子体光栅和介质 - 金属通道。通过调整超表面的垂直和水平结构,我们可以在近红外和中红外区域独立修改超表面的光谱。这种宽带红外超表面展现出强大的光谱调控能力,实现了一种依赖偏振的双共振策略。在第二近红外窗口的折射率传感以及中红外的超灵敏振动光谱方面,它相对于传统金属纳米结构具有竞争优势。具体而言,我们提出的超表面实现了蛋白质浓度传感以及在红外双区域对蛋白质浓度的动态监测。此外,它通过高共振增强了酰胺 II 的中红外吸收。这种结合了波长复用和依赖偏振开关用于蛋白质识别与痕量检测的超表面,为在宽带红外区域开发高性能传感器和集成光子学传感器提供了一种新方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d49/11501136/b87fc6b6faad/j_nanoph-2023-0517_fig_001.jpg

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