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宏观正常结肠镜检查活检中的组织学异常。

Histological abnormalities in biopsies from macroscopically normal colonoscopies.

作者信息

Sanderson I R, Boyle S, Williams C B, Walker-Smith J A

出版信息

Arch Dis Child. 1986 Mar;61(3):274-7. doi: 10.1136/adc.61.3.274.

DOI:10.1136/adc.61.3.274
PMID:3963871
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1777702/
Abstract

One hundred and nineteen children with gastrointestinal symptoms underwent colonoscopy during the course of one year. Out of 39 children that were reported as yielding normal results on endoscopic examination, six had disease detectable only by histology. The pathology included cases of microscopic colitis, Crohn's disease, and indeterminate colitis. To exclude large bowel inflammation as a cause of gastrointestinal symptoms biopsy specimens should always be taken at endoscopy.

摘要

在一年的时间里,119名有胃肠道症状的儿童接受了结肠镜检查。在39名内镜检查报告结果正常的儿童中,有6名儿童的疾病仅通过组织学检查才能检测到。病理情况包括显微镜下结肠炎、克罗恩病和不确定性结肠炎。为排除大肠炎症是胃肠道症状的病因,在内镜检查时应始终取活检标本。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c41/1777702/9e9591d48b7a/archdisch00712-0070-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c41/1777702/d3fa869dd3d7/archdisch00712-0069-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c41/1777702/da527c67218e/archdisch00712-0069-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c41/1777702/688317f38879/archdisch00712-0070-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c41/1777702/9e9591d48b7a/archdisch00712-0070-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c41/1777702/d3fa869dd3d7/archdisch00712-0069-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c41/1777702/da527c67218e/archdisch00712-0069-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c41/1777702/688317f38879/archdisch00712-0070-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c41/1777702/9e9591d48b7a/archdisch00712-0070-b.jpg

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本文引用的文献

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Association of coeliac disease and inflammatory bowel disease.乳糜泻与炎症性肠病的关联。
Gut. 1980 Jul;21(7):636-41. doi: 10.1136/gut.21.7.636.
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Flat small intestinal mucosa and autoantibodies against the gut epithelium.
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Total colonoscopy in children.儿童全结肠镜检查
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The role of mucosal biopsy in the diagnosis of chronic diarrhea: value of multiple biopsies when colonoscopic finding is normal or nonspecific.黏膜活检在慢性腹泻诊断中的作用:结肠镜检查结果正常或非特异性时多次活检的价值
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Diarrhoea caused by collagenous colitis.胶原性结肠炎引起的腹泻。
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Lymphocytic (microscopic) colitis. Clinicopathologic study of 18 patients and comparison to collagenous colitis.
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Autoimmune enteropathy and colitis: is there a generalised autoimmune gut disorder?自身免疫性肠病和结肠炎:是否存在一种全身性自身免疫性肠道疾病?
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Chronic inflammatory bowel disease in childhood.儿童慢性炎症性肠病
Br Med J (Clin Res Ed). 1982 Jan 9;284(6309):101-3. doi: 10.1136/bmj.284.6309.101.
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Colonoscopy in childhood.儿童结肠镜检查
Pediatrics. 1984 May;73(5):594-9.
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Routine colonoscopy service.常规结肠镜检查服务。
Arch Dis Child. 1984 Aug;59(8):790-3. doi: 10.1136/adc.59.8.790.
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An evaluation of the significance of microscopic colitis in patients with chronic diarrhea.慢性腹泻患者微观性结肠炎的意义评估。
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Methane excretion in man--a study of breath, flatus, and faeces.人体甲烷排泄——一项关于呼吸、肠胃气和粪便的研究。
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Specific autoantibodies to gut epithelium in two infants with severe protracted diarrhoea.
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Proctosigmoiditis and coeliac disease.直肠乙状结肠炎与乳糜泻。
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