Rapid Healing of Necrotizing Fasciitis Using the Kerecis Fish Skin Xenograft: A Clinical Case Report.

This case report explores the application of the Kerecis fish skin xenograft, derived from North Atlantic Cod, in treating a large full-thickness wound resulting from necrotizing fasciitis (NF). A 41-year-old female with multiple comorbidities presented with NF of the dorsal forearm and hand. Initially managed with serial washouts with extensive debridement, the remaining dorsal forearm full-thickness wound with exposed tendons was treated with an application of the Kerecis xenograft. The graft facilitated healing, evidenced by rapid epithelialization and decreased pain without the use of additional skin grafting. Traditionally used for chronic conditions, the use of Kerecis in this acute, complex wound highlights its potential for integrating into human tissue and modulating inflammation, as well as acting as an antimicrobial barrier. This case underscores the need for further research into the effectiveness of fish skin xenografts in acute and complex wounds, suggesting a potential shift in emergency wound care practices.