Epidermal Penetration Increases with Age and May Contribute to Systemic Inflammation.
作者信息
Parenteau T Richard, Celli Anna, Zhang Jiechen, Gonzalez Jeanmarie, Meyer Jason M, Abegaze Brook, Piper Merisa L, Elias Peter M, Abuabara Katrina, Grunfeld Carl, Man Mao-Qiang, Scharschmidt Tiffany C, Mauro Theodora M
机构信息
Division of Geriatrics, University of California, San Francisco, San Francisco, California, USA; Bakar Aging Research Institute, University of California, San Francisco, San Francisco, California, USA.
Dermatology Service, San Francisco Veterans Affairs Health Care System, San Francisco, California, USA.
出版信息
J Invest Dermatol. 2025 Jun;145(6):1512-1516.e4. doi: 10.1016/j.jid.2024.12.010. Epub 2024 Dec 31.
Abstract
摘要
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Stratum corneum hydration inversely correlates with certain serum cytokine levels in the elderly, possibly contributing to inflammaging.角质层水合作用与老年人的某些血清细胞因子水平呈负相关，这可能是导致炎症衰老的原因之一。
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Epidermal Dysfunction Leads to an Age-Associated Increase in Levels of Serum Inflammatory Cytokines.表皮功能障碍导致血清炎症细胞因子水平随年龄增长而升高。
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