Adamczyk Jakub, Poziemski Jakub, Siedlecki Pawel
AGH University of Krakow, Department of Computer Science, Cracow, Poland.
Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland.
Sci Data. 2025 Jan 2;12(1):5. doi: 10.1038/s41597-024-04232-w.
The global decline in bee populations poses significant risks to agriculture, biodiversity, and environmental stability. To bridge the gap in existing data, we introduce ApisTox, a comprehensive dataset focusing on the toxicity of pesticides to honey bees (Apis mellifera). This dataset combines and leverages data from existing sources such as ECOTOX and PPDB, providing an extensive, consistent, and curated collection that surpasses the previous datasets. ApisTox incorporates a wide array of data, including toxicity levels for chemicals, details such as time of their publication in literature, and identifiers linking them to external chemical databases. This dataset may serve as an important tool for environmental and agricultural research, but also can support the development of policies and practices aimed at minimizing harm to bee populations. Finally, ApisTox offers a unique resource for benchmarking molecular property prediction methods on agrochemical compounds, facilitating advancements in both environmental science and chemoinformatics. This makes it a valuable tool for both academic research and practical applications in bee conservation.
全球蜜蜂数量的减少给农业、生物多样性和环境稳定性带来了重大风险。为了填补现有数据的空白，我们引入了ApisTox，这是一个专注于农药对蜜蜂（西方蜜蜂）毒性的综合数据集。该数据集整合并利用了来自ECOTOX和PPDB等现有来源的数据，提供了一个广泛、一致且经过整理的集合，超越了以往的数据集。ApisTox包含了大量数据，包括化学物质的毒性水平、它们在文献中发表的时间等细节，以及将它们与外部化学数据库链接的标识符。这个数据集不仅可以作为环境和农业研究的重要工具，还可以支持旨在尽量减少对蜜蜂种群危害的政策和实践的制定。最后，ApisTox为农用化学品化合物的分子性质预测方法提供了一个独特的基准资源，促进了环境科学和化学信息学的进步。这使其成为蜜蜂保护学术研究和实际应用的宝贵工具。
