Nahiduzzaman Md, Abdulrazak Lway Faisal, Kibria Hafsa Binte, Khandakar Amith, Ayari Mohamed Arselene, Ahamed Md Faysal, Ahsan Mominul, Haider Julfikar, Moni Mohammad Ali, Kowalski Marcin
Department of Electrical and Computer Engineering, Rajshahi University of Engineering and Technology, Rajshahi, 6204, Bangladesh.
Department of Space Technology Engineering, Electrical Engineering Technical College, Middle Technical University, Baghdad, Iraq.
Sci Rep. 2025 Jan 10;15(1):1649. doi: 10.1038/s41598-025-85874-7.
Brain tumors present a significant global health challenge, and their early detection and accurate classification are crucial for effective treatment strategies. This study presents a novel approach combining a lightweight parallel depthwise separable convolutional neural network (PDSCNN) and a hybrid ridge regression extreme learning machine (RRELM) for accurately classifying four types of brain tumors (glioma, meningioma, no tumor, and pituitary) based on MRI images. The proposed approach enhances the visibility and clarity of tumor features in MRI images by employing contrast-limited adaptive histogram equalization (CLAHE). A lightweight PDSCNN is then employed to extract relevant tumor-specific patterns while minimizing computational complexity. A hybrid RRELM model is proposed, enhancing the traditional ELM for improved classification performance. The proposed framework is compared with various state-of-the-art models in terms of classification accuracy, model parameters, and layer sizes. The proposed framework achieved remarkable average precision, recall, and accuracy values of 99.35%, 99.30%, and 99.22%, respectively, through five-fold cross-validation. The PDSCNN-RRELM outperformed the extreme learning machine model with pseudoinverse (PELM) and exhibited superior performance. The introduction of ridge regression in the ELM framework led to significant enhancements in classification performance model parameters and layer sizes compared to those of the state-of-the-art models. Additionally, the interpretability of the framework was demonstrated using Shapley Additive Explanations (SHAP), providing insights into the decision-making process and increasing confidence in real-world diagnosis.
脑肿瘤是一项重大的全球健康挑战,其早期检测和准确分类对于有效的治疗策略至关重要。本研究提出了一种新颖的方法,将轻量级并行深度可分离卷积神经网络(PDSCNN)和混合岭回归极限学习机(RRELM)相结合,用于基于MRI图像准确分类四种类型的脑肿瘤(胶质瘤、脑膜瘤、无肿瘤和垂体瘤)。所提出的方法通过采用对比度受限自适应直方图均衡化(CLAHE)提高了MRI图像中肿瘤特征的可见性和清晰度。然后使用轻量级PDSCNN提取相关的肿瘤特异性模式,同时将计算复杂度降至最低。提出了一种混合RRELM模型,改进了传统的极限学习机以提高分类性能。在所提出的框架在分类准确率、模型参数和层大小方面与各种先进模型进行了比较。通过五折交叉验证,所提出的框架分别实现了99.35%、99.30%和99.22%的显著平均精度、召回率和准确率值。PDSCNN-RRELM优于带伪逆的极限学习机模型(PELM),并表现出卓越的性能。与先进模型相比,在极限学习机框架中引入岭回归导致分类性能、模型参数和层大小有显著提升。此外,使用Shapley加法解释(SHAP)证明了该框架的可解释性,为决策过程提供了见解,并增加了对实际诊断的信心。