Theobald Paula, Herold Fabian, Gronwald Thomas, Müller Notger G
Research Group Degenerative and Chronic Diseases, Movement, Faculty of Health Sciences Brandenburg, University of Potsdam, Potsdam, Germany.
Institute of Interdisciplinary Exercise Science and Sports Medicine, MSH Medical School Hamburg, Hamburg, Germany.
J Alzheimers Dis. 2025 Feb;103(4):1005-1009. doi: 10.1177/13872877241307407. Epub 2025 Jan 15.
The motoric cognitive risk syndrome (MCR) is a novel and clinically relevant pre-dementia syndrome indicating a higher dementia risk (e.g., for Alzheimer's disease). Given that MCR prevalence is unknown in Germany, we conducted a cross-sectional study, in which 208 participants from Germany aged 50 and 82 years answered an online survey including questions to assess subjective MCR (sMCR). The adjusted sMCR prevalence was 25.3%. Adults with sMCR reported more diseases and showed negative associations with physical activity, sedentary behavior, and sleep, suggesting that lifestyle modifications can play a significant role in MCR prevention. Further research is required to complement our preliminary findings on sMCR prevalence in Germany.
运动认知风险综合征（MCR）是一种新型的、具有临床相关性的痴呆前综合征，提示痴呆风险较高（如阿尔茨海默病）。鉴于德国MCR的患病率未知，我们开展了一项横断面研究，208名年龄在50至82岁之间的德国参与者回答了一项在线调查，其中包括评估主观MCR（sMCR）的问题。调整后的sMCR患病率为25.3%。患有sMCR的成年人报告有更多疾病，并且与身体活动、久坐行为和睡眠呈负相关，这表明生活方式的改变在预防MCR方面可发挥重要作用。需要进一步的研究来补充我们关于德国sMCR患病率的初步研究结果。
