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缩小全氟和多氟烷基物质毒理学与代谢研究的认知差距

Closing the Gaps in Understanding PFAS Toxicology and Metabolism.

作者信息

MacMillan Denise K, Wetmore Barbara A, Dasgupta Subham, Baldwin William S

机构信息

Center for Computational Toxicology and Exposure, Office of Research and Development, U.S. Environmental Protection Agency (EPA), Durham, NC 27709, USA.

Department of Biological Sciences, Clemson University, Clemson, SC 29634, USA.

出版信息

Toxics. 2024 Dec 27;13(1):19. doi: 10.3390/toxics13010019.

DOI:10.3390/toxics13010019
PMID:39853019
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11769177/
Abstract

Per- and polyfluoroalkyl substances (PFAS) are nearly ubiquitous and found in rivers, soils, atmosphere, food packaging, clothing, cosmetics, commercial products, homes, drinking water, and humans and other organisms [...].

摘要

全氟和多氟烷基物质(PFAS)几乎无处不在,存在于河流、土壤、大气、食品包装、衣物、化妆品、商业产品、家庭、饮用水以及人类和其他生物体中[……]。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34cf/11769177/385f4e820d78/toxics-13-00019-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34cf/11769177/385f4e820d78/toxics-13-00019-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34cf/11769177/385f4e820d78/toxics-13-00019-g001.jpg

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Neurotoxic Effects of Mixtures of Perfluoroalkyl Substances (PFAS) at Environmental and Human Blood Concentrations.环境浓度和人体血液浓度下全氟烷基物质(PFAS)混合物的神经毒性效应
Environ Sci Technol. 2024 Sep 11;58(38):16774-84. doi: 10.1021/acs.est.4c06017.
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Using Zebrafish to Screen Developmental Toxicity of Per- and Polyfluoroalkyl Substances (PFAS).
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High-Resolution Mass Spectrometry for Human Exposomics: Expanding Chemical Space Coverage.高分辨率质谱技术在人类暴露组学中的应用:拓展化学空间覆盖范围。
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