慢性病成年患者中与疲劳、身体活动及活动节奏相关的健康相关生活质量。
Health-related quality of life associated with fatigue, physical activity and activity pacing in adults with chronic conditions.
作者信息
Barakou Ioulia, Seves Bregje L, Abonie Ulric S, Finch Tracy, Hackett Kate L, Hettinga Florentina J
机构信息
Department of Nursing, Midwifery & Health, Northumbria University, Newcastle upon Tyne, UK.
Department of Sport Exercise and Rehabilitation, Northumbria University, Newcastle upon Tyne, UK.
出版信息
BMC Sports Sci Med Rehabil. 2025 Jan 28;17(1):13. doi: 10.1186/s13102-025-01057-x.
BACKGROUND
Fatigue and inactivity are linked to decreased health-related quality of life (HRQoL) in chronic conditions. A multidimensional approach to activity pacing may improve HRQoL by promoting physical activity (PA) and alleviating fatigue. Addressing fatigue across chronic conditions is crucial, especially when underlying causes are unknown. This study aimed to (1) examine associations between HRQoL, fatigue, pacing, risk of overactivity, PA, and self-regulation of PA in adults with chronic conditions and (2) examine if these associations differ across HRQoL domains: physical, social, emotional, and functional well-being.
METHODS
Sixty-six adults with chronic conditions were recruited from UK fatigue clinics and the community. HRQoL, pacing, risk of overactivity, PA, and self-regulation of PA were assessed with standardised questionnaires and Actigraph monitor. Associations were analysed with linear mixed models, correcting for confounders.
RESULTS
HRQoL was significantly associated with fatigue (B=-7.82), pacing (B=-0.23), and self-regulation of PA (B = 0.11). Interaction effects revealed fatigue's impact on HRQoL varied significantly in physical (β=-13.49), social (β=-6.81), and emotional (β=-4.10) domains. Pacing showed significant differences in physical (β=-0.49), social (β=-7.12), and emotional (β=-7.45) domains. Perceived overactivity differed in social domain (β=-6.27), while device-based PA differed in physical (β = 0.35) and social (β = 5.73).
CONCLUSION
The negative association between fatigue and HRQoL underscores the importance of effective fatigue management. Higher pacing engagement and lower HRQoL may indicate higher fatigue. Positive associations between self-regulation and PA with HRQoL emphasise benefits of appropriate PA behaviours. The stronger impact of decreased fatigue, increased pacing, and PA on physical well-being suggests a multidimensional fatigue management approach.
背景
在慢性疾病中，疲劳和活动不足与健康相关生活质量（HRQoL）下降有关。一种多维度的活动节奏调整方法可能通过促进身体活动（PA）和减轻疲劳来改善HRQoL。解决慢性疾病中的疲劳问题至关重要，尤其是在潜在病因不明的情况下。本研究旨在：（1）检查患有慢性疾病的成年人中HRQoL、疲劳、节奏调整、活动过度风险、PA及PA自我调节之间的关联；（2）检查这些关联在HRQoL各领域（身体、社会、情感和功能健康）中是否存在差异。
方法
从英国疲劳诊所和社区招募了66名患有慢性疾病的成年人。使用标准化问卷和Actigraph监测仪评估HRQoL、节奏调整、活动过度风险、PA及PA自我调节。采用线性混合模型分析关联，并对混杂因素进行校正。
结果
HRQoL与疲劳（B=-7.82）、节奏调整（B=-0.23）及PA自我调节（B = 0.11）显著相关。交互作用表明，疲劳对HRQoL的影响在身体（β=-13.49）、社会（β=-6.81）和情感（β=-4.10）领域存在显著差异。节奏调整在身体（β=-0.49）、社会（β=-7.12）和情感（β=-7.45）领域存在显著差异。感知到的活动过度在社会领域存在差异（β=-6.27），而基于设备的PA在身体（β = 0.35）和社会（β = 5.73）领域存在差异。
结论
疲劳与HRQoL之间的负相关强调了有效管理疲劳的重要性。更高的节奏调整参与度和更低的HRQoL可能表明更高的疲劳程度。自我调节和PA与HRQoL之间的正相关强调了适当PA行为的益处。疲劳减轻、节奏调整增加和PA对身体健康的更强影响表明需要采用多维度的疲劳管理方法。
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