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铥激光辅助腹腔镜治疗复发性化脓性胆管炎肝内结石:一例报告及微创治疗方法综述

Thulium laser-assisted laparoscopic management of intrahepatic stones in recurrent pyogenic cholangitis: A case report and review of minimally invasive approaches.

作者信息

Yodying Hariruk

机构信息

Department of Surgery, HRH Princess MahaChakri Sirindhorn Medical Center, Faculty of Medicine, Srinakharinwirot University, Nakhon Nayok, Thailand.

出版信息

Int J Surg Case Rep. 2025 Mar;128:111005. doi: 10.1016/j.ijscr.2025.111005. Epub 2025 Feb 2.

DOI:10.1016/j.ijscr.2025.111005
PMID:39908930
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11847040/
Abstract

INTRODUCTION

Recurrent pyogenic cholangitis (RPC) presents significant management challenges, particularly when complicated by large intrahepatic stones. While thulium laser technology has demonstrated excellent results in urological stone treatment, its application in biliary stones remains relatively unexplored. We present a novel approach utilizing laparoscopic choledochoscopy with thulium laser lithotripsy for managing intrahepatic stones in RPC.

CASE PRESENTATION

A 65-year-old female presented with a two-year history of recurrent right upper quadrant pain, fever, and jaundice. Diagnostic imaging revealed multiple large intrahepatic stones without any liver atrophy or mass lesions. After initial ERCP for acute cholangitis management, the patient underwent laparoscopic choledochoscopy with thulium laser lithotripsy. The procedure included stone fragmentation, extraction, and choledochoduodenostomy for long-term biliary drainage. The procedure was successfully completed with minimal blood loss and no intraoperative complications. At 6-month follow-up, the patient remained asymptomatic with normal liver function, despite small retained stones.

DISCUSSION

This approach combines the benefits of minimally invasive surgery with advanced laser technology. Thulium laser offers potential advantages over conventional lithotripsy methods, including enhanced precision and reduced risk of bile duct injury. The successful outcome in this case suggests that this technique may be a viable option for complex hepatolithiasis in RPC.

CONCLUSION

Laparoscopic choledochoscopy with thulium laser lithotripsy represents a promising minimally invasive option for managing intrahepatic stones in RPC. While our case demonstrates technical feasibility, long-term follow-up and larger studies are needed to fully evaluate its efficacy.

摘要

引言

复发性化脓性胆管炎(RPC)带来了重大的治疗挑战,尤其是在合并肝内大结石时。虽然铥激光技术在泌尿系统结石治疗中已显示出优异效果,但其在胆管结石治疗中的应用仍相对未被充分探索。我们介绍一种利用腹腔镜胆管镜联合铥激光碎石术治疗RPC肝内结石的新方法。

病例报告

一名65岁女性,有两年复发性右上腹疼痛、发热和黄疸病史。诊断性影像学检查显示多个肝内大结石,无肝萎缩或占位性病变。在最初进行内镜逆行胰胆管造影(ERCP)以治疗急性胆管炎后,患者接受了腹腔镜胆管镜联合铥激光碎石术。该手术包括结石破碎、取出,以及行胆总管十二指肠吻合术以进行长期胆管引流。手术成功完成,失血极少,无术中并发症。随访6个月时,尽管有小的残留结石,但患者无症状,肝功能正常。

讨论

这种方法结合了微创手术和先进激光技术的优点。铥激光与传统碎石方法相比具有潜在优势,包括更高的精确性和降低胆管损伤风险。该病例的成功结果表明,这种技术可能是RPC复杂肝内胆管结石的一种可行选择。

结论

腹腔镜胆管镜联合铥激光碎石术是治疗RPC肝内结石的一种有前景的微创选择。虽然我们的病例证明了技术可行性,但需要长期随访和更大规模的研究来全面评估其疗效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cf5/11847040/d081370adced/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cf5/11847040/2e5fab15ab1d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cf5/11847040/7ab2a0984319/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cf5/11847040/0e27d9f757dc/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cf5/11847040/15f3d8d3f7de/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cf5/11847040/d081370adced/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cf5/11847040/2e5fab15ab1d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cf5/11847040/7ab2a0984319/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cf5/11847040/0e27d9f757dc/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cf5/11847040/15f3d8d3f7de/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cf5/11847040/d081370adced/gr5.jpg

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