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使用具有边界感知骰子损失的深度学习改进肺部超声中的A线和B线检测

Improved A-Line and B-Line Detection in Lung Ultrasound Using Deep Learning with Boundary-Aware Dice Loss.

作者信息

Abbasi Soolmaz, Wahd Assefa Seyoum, Ghosh Shrimanti, Ezzelarab Maha, Panicker Mahesh, Chen Yale Tung, Jaremko Jacob L, Hareendranathan Abhilash

机构信息

Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, AB T6G 2R3, Canada.

Infocomm Technology Cluster, Singapore Institute of Technology, Singapore 828608, Singapore.

出版信息

Bioengineering (Basel). 2025 Mar 18;12(3):311. doi: 10.3390/bioengineering12030311.

DOI:10.3390/bioengineering12030311
PMID:40150775
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11939577/
Abstract

Lung ultrasound (LUS) is a non-invasive bedside imaging technique for diagnosing pulmonary conditions, especially in critical care settings. A-lines and B-lines are important features in LUS images that help to assess lung health and identify changes in lung tissue. However, accurately detecting and segmenting these lines remains challenging, due to their subtle blurred boundaries. To address this, we propose TransBound-UNet, a novel segmentation model that integrates a transformer-based encoder with boundary-aware Dice loss to enhance medical image segmentation. This loss function incorporates boundary-specific penalties into a hybrid Dice-BCE formulation, allowing for more accurate segmentation of critical structures. The proposed framework was tested on a dataset of 4599 LUS images. The model achieved a Dice Score of 0.80, outperforming state-of-the-art segmentation networks. Additionally, it demonstrated superior performance in Specificity (0.97) and Precision (0.85), with a significantly reduced Hausdorff Distance of 15.13, indicating improved boundary delineation and overall segmentation quality. Post-processing techniques were applied to automatically detect and count A-lines and B-lines, demonstrating the potential of the segmented outputs in diagnostic workflows. This framework provides an efficient solution for automated LUS interpretation, with improved boundary precision.

摘要

肺部超声(LUS)是一种用于诊断肺部疾病的非侵入性床边成像技术,尤其适用于重症监护环境。A线和B线是LUS图像中的重要特征,有助于评估肺部健康状况并识别肺组织的变化。然而,由于它们的边界细微模糊,准确检测和分割这些线仍然具有挑战性。为了解决这个问题,我们提出了TransBound-UNet,一种新颖的分割模型,它将基于Transformer的编码器与边界感知Dice损失相结合,以增强医学图像分割。这种损失函数将特定于边界的惩罚纳入混合Dice-BCE公式中,从而能够更准确地分割关键结构。所提出的框架在一个包含4599张LUS图像的数据集上进行了测试。该模型的Dice分数达到了0.80,优于现有最先进的分割网络。此外,它在特异性(0.97)和精度(0.85)方面表现出色,豪斯多夫距离显著降低至15.13,表明边界描绘和整体分割质量得到了改善。后处理技术被应用于自动检测和计数A线和B线,展示了分割输出在诊断工作流程中的潜力。该框架为自动LUS解读提供了一种高效的解决方案,具有更高的边界精度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfbc/11939577/d3d74fcfed1f/bioengineering-12-00311-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfbc/11939577/f712d610f80c/bioengineering-12-00311-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfbc/11939577/6c8af33de9f6/bioengineering-12-00311-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfbc/11939577/bc88c1084cf2/bioengineering-12-00311-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfbc/11939577/d3d74fcfed1f/bioengineering-12-00311-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfbc/11939577/f712d610f80c/bioengineering-12-00311-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfbc/11939577/6c8af33de9f6/bioengineering-12-00311-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfbc/11939577/bc88c1084cf2/bioengineering-12-00311-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfbc/11939577/d3d74fcfed1f/bioengineering-12-00311-g004.jpg

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本文引用的文献

1
Enhancing Lung Ultrasound Diagnostics: A Clinical Study on an Artificial Intelligence Tool for the Detection and Quantification of A-Lines and B-Lines.增强肺部超声诊断:一项关于用于检测和量化A线与B线的人工智能工具的临床研究。
Diagnostics (Basel). 2024 Nov 12;14(22):2526. doi: 10.3390/diagnostics14222526.
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Active learning based on multi-enhanced views for classification of multiple patterns in lung ultrasound images.
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An Integrated Approach using YOLOv8 and ResNet, SeResNet & Vision Transformer (ViT) Algorithms based on ROI Fracture Prediction in X-ray Images of the Elbow.基于 ROI 骨折预测的肘部 X 射线图像的 YOLOv8 和 ResNet、SeResNet 和 Vision Transformer(ViT)算法的综合方法。
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Deep learning for real-time multi-class segmentation of artefacts in lung ultrasound.用于肺部超声伪像实时多类分割的深度学习
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Point-of-care ultrasound use in COVID-19: a narrative review.即时超声在2019冠状病毒病中的应用:一项叙述性综述。
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A Review of Deep Learning Applications in Lung Ultrasound Imaging of COVID-19 Patients.新型冠状病毒肺炎患者肺部超声成像中深度学习应用的综述
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Improving Anatomical Plausibility in Medical Image Segmentation via Hybrid Graph Neural Networks: Applications to Chest X-Ray Analysis.通过混合图神经网络提高医学图像分割的解剖合理性:在胸部 X 光分析中的应用。
IEEE Trans Med Imaging. 2023 Feb;42(2):546-556. doi: 10.1109/TMI.2022.3224660. Epub 2023 Feb 2.
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Automatic detection of A-line in lung ultrasound images using deep learning and image processing.使用深度学习和图像处理自动检测肺部超声图像中的 A 线。
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A novel unsupervised approach based on the hidden features of Deep Denoising Autoencoders for COVID-19 disease detection.一种基于深度去噪自编码器隐藏特征的新型无监督方法用于新冠疾病检测。
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