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喀麦隆对具有大流行潜力的甲型流感和中东呼吸综合征冠状病毒在人体中的调查。

Investigation of influenza A of pandemic potential and MERS-Coronavirus in humans in Cameroon.

作者信息

Monamele Chavely Gwladys, Njankouo Ripa Mohamadou, Yogne Christian Nsangou, Essengue Loique Landry Messanga, Bilounga Chanceline Ndongo, Tsafack Desmon Toutou, Njifon Hermann Landry Munshili, Tamoufe Ubald, Perraut Ronald, Njouom Richard

机构信息

Virology Service, Centre Pasteur of Cameroon, PO Box 1274, Yaounde, Cameroon.

Faculty of Health Sciences, University of Buea, PO Box 63, Buea, Cameroon.

出版信息

BMC Res Notes. 2025 Mar 31;18(1):133. doi: 10.1186/s13104-025-07179-2.

Abstract

OBJECTIVE

According to the World Health Organization, surveillance for respiratory viruses with pandemic potential should be included in routine surveillance to be on alert for zoonotic transmission. This study reports on data from the surveillance of influenza A/H5, influenza A/H7 and MERS-Coronavirus in Cameroon.

RESULTS

A total of 855 participants were enrolled. Of these, 11.7% were positive for influenza A and none were positive for influenza A/H5, A/H7 and MERS-Coronavirus. Most participants (77.1%) were enrolled within 5 days of illness onset and the younger population under 2 years of age (31.4%) was the most represented. In terms of clinical manifestations, the majority had flu-like symptoms including fever, cough, rhinorrhoea, asthenia, shortness of breath, noisy breathing and headache. These results are important to fill the knowledge gap on the epidemiology of influenza A/H5, A/H7 and MERS-Coronavirus in humans, for which information is lacking in several countries.

摘要

目的

根据世界卫生组织的建议,应对具有大流行潜力的呼吸道病毒进行监测,并将其纳入常规监测,以警惕人畜共患病传播。本研究报告了喀麦隆对甲型H5流感、甲型H7流感和中东呼吸综合征冠状病毒监测的数据。

结果

共纳入855名参与者。其中,11.7%的甲型流感检测呈阳性,甲型H5流感、甲型H7流感和中东呼吸综合征冠状病毒检测均为阴性。大多数参与者(77.1%)在发病后5天内被纳入研究,2岁以下的年轻人群占比最高(31.4%)。在临床表现方面,大多数人有流感样症状,包括发热、咳嗽、流鼻涕、乏力、呼吸急促、呼吸声粗和头痛。这些结果对于填补一些国家缺乏的关于甲型H5流感、甲型H7流感和中东呼吸综合征冠状病毒在人群中流行病学的知识空白具有重要意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c13b/11959992/81ef174b87a2/13104_2025_7179_Fig1_HTML.jpg

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