Q热心内膜炎治疗期间循环免疫复合物浓度和抗体滴度的变化。
Changes in circulating immune complex concentrations and antibody titres during treatment of Q fever endocarditis.
作者信息
Coyle P V, Thompson J, Adgey A A, Rutter D A, Fay A, McNeill T A, Connolly J H
出版信息
J Clin Pathol. 1985 Jul;38(7):743-6. doi: 10.1136/jcp.38.7.743.
Abstract
Serum samples from 20 patients with Q fever endocarditis were tested for the presence of circulating immune complexes to see whether their concentrations correlated with antibody titres during treatment and whether they could be used to monitor the response to antimicrobial treatment. Circulating immune complexes were found in all 20 patients. The concentrations in 15 patients correlated with either or both of the Q fever phase 1 and phase 2 antibody titres obtained during treatment. In the other five patients no correlation with the antibody titres was found. There was no association between circulating immune complex concentrations and clinical response to treatment.
摘要
对20例Q热心内膜炎患者的血清样本进行检测，以确定循环免疫复合物的存在，观察其浓度在治疗期间是否与抗体滴度相关，以及它们是否可用于监测对抗菌治疗的反应。所有20例患者均检测到循环免疫复合物。15例患者的循环免疫复合物浓度与治疗期间获得的Q热1期和2期抗体滴度中的一项或两项相关。在另外5例患者中，未发现与抗体滴度相关。循环免疫复合物浓度与治疗的临床反应之间无关联。
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本文引用的文献
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