Okui Nobuo
Urogynecology, Yokosuka Urogynecology and Urology Clinic, Kanagawa, JPN.
Mathematics, Kanagawa Dental University, Kanagawa, JPN.
Cureus. 2025 Mar 16;17(3):e80650. doi: 10.7759/cureus.80650. eCollection 2025 Mar.
Background Stress urinary incontinence (SUI) is common among older women and may be associated with frailty. Frailty, characterized by reduced physiological reserves and muscle weakness, can impair pelvic floor function and increase the risk of SUI. This study evaluates the association between frailty and SUI using a large dataset. Methods Data from the National Health and Nutrition Examination Survey (NHANES), 2005-2018 were analyzed, including 6,386 women aged ≥20 years with complete frailty and SUI data. Frailty was classified using NHANES-derived criteria. SUI was assessed through self-reported questionnaires. Propensity score matching adjusted for confounders. Logistic regression and Bayesian modeling were applied to evaluate associations. Results SUI prevalence was higher in frail individuals (607 (32.0%) vs. 414 (15.0%), p < 0.001). Frailty independently predicted SUI (OR 1.48; 95% CI 1.25-1.75; p < 0.001). Bayesian modeling demonstrated interconnections between frailty, SUI, and functional limitations. Conclusions Frailty is a significant predictor of SUI in women. Identifying frailty status may improve SUI risk stratification and guide targeted interventions.
压力性尿失禁（SUI）在老年女性中很常见，可能与身体虚弱有关。身体虚弱的特征是生理储备减少和肌肉无力，会损害盆底功能并增加患SUI的风险。本研究使用大型数据集评估身体虚弱与SUI之间的关联。方法：分析了2005年至2018年美国国家健康与营养检查调查（NHANES）的数据，包括6386名年龄≥20岁且有完整身体虚弱和SUI数据的女性。身体虚弱采用NHANES得出的标准进行分类。SUI通过自我报告问卷进行评估。倾向得分匹配用于调整混杂因素。应用逻辑回归和贝叶斯模型来评估关联。结果：身体虚弱者的SUI患病率更高（607例（32.0%）对414例（15.0%），p<0.001）。身体虚弱独立预测SUI（OR 1.48；95%CI 1.25 - 1.75；p<0.001）。贝叶斯模型显示了身体虚弱、SUI和功能受限之间的相互联系。结论：身体虚弱是女性SUI的重要预测因素。识别身体虚弱状态可能会改善SUI风险分层并指导针对性干预。
