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庆祝国立糖尿病、消化和肾脏疾病研究所(NIDDK)支持的专注于糖尿病、内分泌学和代谢性疾病的研究中心的过去、现在和未来。

Celebrating the Past, Present, and Future of NIDDK-Supported Research Centers Focused on Diabetes, Endocrinology, and Metabolic Diseases.

作者信息

Silva Corinne M, Thornton Pamela L, Artis Dickerson Shavon, Eggerman Thomas L, Laughlin Maren R, Wallace Julie A, Hanlon-Tilghman Mary C, Cefalu William T

机构信息

National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD.

出版信息

Diabetes. 2025 Jul 1;74(7):1099-1106. doi: 10.2337/db25-0039.

DOI:10.2337/db25-0039
PMID:40272256
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12185955/
Abstract

UNLABELLED

This year marks the 75th anniversary of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health. NIDDK's long history of research and innovation includes support of four types of collaborative research centers focused on diabetes, endocrinology, and metabolic diseases. The Diabetes Research Centers promote basic and clinical diabetes research, while the Centers for Diabetes Translation Research conduct diabetes research across the translation science spectrum. The Mouse Metabolic Phenotyping Center (MMPC)-Live program provides the research community with standardized phenotyping services for mouse models of diabetes and obesity, and the Cystic Fibrosis Research and Translation Centers advance basic, preclinical, and clinical research for cystic fibrosis. These centers have evolved over time in response to new scientific opportunities and to expand their reach to be an asset to the larger scientific community. Looking to the future, NIDDK will continue to ensure that these centers enhance the research community, foster novel and synergistic scientific collaborations, and promote career development of scientists in the early stages of their careers. We will also ensure that our centers align with NIDDK's goal of improving health outcomes for all people with and at risk for diseases, within our mission.

ARTICLE HIGHLIGHTS

NIDDK's research centers focused on diabetes, endocrinology, and metabolism serve broad communities of investigators and address existing research gaps to propel scientific progress. The Diabetes Research Centers support basic and clinical research, and the Centers for Diabetes Translation Research support research across the translation science spectrum. The MMPC-Live program provides phenotyping services for mouse models of diabetes and obesity, and the Cystic Fibrosis Research and Translation Centers advance basic, preclinical, and clinical research for cystic fibrosis. Future goals for the centers include fostering novel and synergistic scientific collaborations, as well as continuing to promote career development.

摘要

未标注

今年是美国国立卫生研究院国家糖尿病、消化和肾脏疾病研究所(NIDDK)成立75周年。NIDDK悠久的研究与创新历史包括对四类专注于糖尿病、内分泌学和代谢疾病的合作研究中心的支持。糖尿病研究中心促进糖尿病基础和临床研究,而糖尿病转化研究中心则在转化科学领域开展糖尿病研究。小鼠代谢表型分析中心(MMPC)-实时项目为糖尿病和肥胖小鼠模型的研究群体提供标准化表型分析服务,囊性纤维化研究与转化中心推进囊性纤维化的基础、临床前和临床研究。随着时间的推移,这些中心不断发展,以应对新的科学机遇,并扩大其影响力,成为更广泛科学界的一项资产。展望未来,NIDDK将继续确保这些中心加强研究群体建设,促进新颖且协同的科学合作,并推动处于职业生涯早期阶段的科学家的职业发展。我们还将确保我们的中心在我们的使命范围内,与NIDDK改善所有患有疾病和有患病风险人群健康结果的目标保持一致。

文章亮点

NIDDK专注于糖尿病、内分泌学和代谢的研究中心服务于广泛的研究人员群体,填补现有研究空白以推动科学进步。糖尿病研究中心支持基础和临床研究,糖尿病转化研究中心支持跨转化科学领域的研究。MMPC-实时项目为糖尿病和肥胖小鼠模型提供表型分析服务,囊性纤维化研究与转化中心推进囊性纤维化的基础、临床前和临床研究。这些中心未来的目标包括促进新颖且协同的科学合作,以及继续推动职业发展。

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