Wang Zhe, Xiao Junbo, Liu Hanzhao, Zheng Ziru, Zhang Yifei, Liu Yingying, Li Pengfei
State Key Laboratory of Green Pesticide, College of Plant Protection, South China Agricultural University, Guangzhou, 510642, China.
Engineering Research Center of Biological Control, Ministry of Education, Guangzhou, 510642, China.
Arch Virol. 2025 May 16;170(6):132. doi: 10.1007/s00705-025-06310-9.
In this study, we identified a novel mitovirus, designated as "Pleurotus pulmonarius duamitovirus 1" (PpDMV1), from the edible fungus Pleurotus pulmonarius. Genome sequencing revealed a 2,622-nucleotide (nt) genome containing a single 2,001-nt open reading frame (ORF) encoding an RNA-dependent RNA polymerase (RdRp). Full-length genome sequence comparisons using BLASTx demonstrated the closest sequence similarity (56.68% identity) to Erysiphe necator associated mitovirus 15 (EnMV15). Phylogenetic analysis positioned PpDMV1 within the genus Duamitovirus (family Mitoviridae). To our knowledge, this is the first report of a mitovirus infection in P. pulmonarius.
在本研究中，我们从食用菌肺形侧耳中鉴定出一种新型的线粒体病毒，命名为“肺形侧耳双粒病毒1”（PpDMV1）。基因组测序显示，该病毒基因组为2622个核苷酸（nt），包含一个单一的2001个nt的开放阅读框（ORF），编码一种RNA依赖的RNA聚合酶（RdRp）。使用BLASTx进行的全长基因组序列比较显示，其与葡萄白粉菌相关线粒体病毒15（EnMV15）的序列相似性最高（同一性为56.68%）。系统发育分析将PpDMV1定位在双粒病毒属（线粒体病毒科）内。据我们所知，这是关于肺形侧耳中线粒体病毒感染的首次报道。
