Akanda Md Khokon Miah, Hasan A H M Nazmul, Mehjabin Sanzia, Parvez G M Masud, Yasmin Sabina, Akhtar Md Sayeed, Anjum Saistha, Ashique Sumel, Sulatana Rokeya, Ansari Mohammad Yousuf
Department of Pharmacy, University of Asia Pacific, Dhaka, 1205, Bangladesh.
Department of Pharmacy, Varendra University, Rajshahi, 6204, Bangladesh.
Inflammopharmacology. 2025 May 20. doi: 10.1007/s10787-025-01780-4.
Plants and their compounds are extensively utilized in various industries, including pharmacy, medicine, food, and cosmetics, making the papaya (Carica papaya) fruit tree economically vital in tropical and subtropical regions. This review provides detailed information on the traditional uses, nutritional content, phytochemistry, and pharmacological activity of C. papaya. The authors conducted a comprehensive search using databases like Scopus, PubMed, Scilit, and Google Scholar to gather relevant articles on this title. Papaya extract is commonly used to treat various health issues, including inflammation and pain, hypertension, diabetes, dermatitis, asthma, and stomach problems due to its rich chemical compositions of flavonoids, steroids, sterol, and β-sitosterol. C. papaya extracts exhibit numerous properties anti-inflammatory, anti-ulcer, anti-arthritic, analgesic, anti-fertility, anti-cancer, anti-bacterial, antiviral, wound-healing, etc. in both laboratory and animal studies. C. papaya may contain new active compounds for treating various ailments, but toxicity, efficacy, and clinical trials are needed before its therapeutic use.
植物及其化合物在包括制药、医学、食品和化妆品在内的各个行业中得到广泛应用，这使得番木瓜（番木瓜属）果树在热带和亚热带地区具有重要的经济价值。本综述提供了关于番木瓜的传统用途、营养成分、植物化学和药理活性的详细信息。作者使用Scopus、PubMed、Scilit和谷歌学术等数据库进行了全面搜索，以收集有关该主题的相关文章。番木瓜提取物由于其富含黄酮类、甾体、甾醇和β-谷甾醇等化学成分，常用于治疗各种健康问题，包括炎症和疼痛、高血压、糖尿病、皮炎、哮喘和胃部问题。在实验室和动物研究中，番木瓜提取物均表现出多种特性，如抗炎、抗溃疡、抗关节炎、止痛、抗生育、抗癌、抗菌、抗病毒、伤口愈合等。番木瓜可能含有用于治疗各种疾病的新活性化合物，但在其用于治疗之前，需要进行毒性、疗效和临床试验。
