Hawkins D A, Wilson R S, Thomas B J, Evans R T
Br J Ophthalmol. 1985 Sep;69(9):640-4. doi: 10.1136/bjo.69.9.640.
The use of fluorescein-conjugated monoclonal antibody (Syva, UK) provided a rapid reliable diagnostic test for Chlamydia trachomatis in conjunctival samples from 100 adults with acute follicular conjunctivitis and seven babies with suspected chlamydial ophthalmia neonatorum. Elementary bodies (EBs) were seen in smears from 11 of the adults, and culture confirmed C. trachomatis infection in nine of them. Both tests were positive with specimens from four of the neonates. No specimens from either group of patients produced a negative result in the smear test but a positive result by culture. However, the two adult patients with chlamydial ophthalmia who had negative cultures but were EB-positive had both had prior topical tetracycline therapy.
使用荧光素结合单克隆抗体（Syva，英国）对100例患有急性滤泡性结膜炎的成人以及7例疑似衣原体性新生儿眼炎的婴儿的结膜样本进行沙眼衣原体检测，提供了一种快速可靠的诊断方法。在11例成人的涂片样本中发现了原体（EBs），其中9例经培养确诊为沙眼衣原体感染。两组新生儿的4份样本两种检测均呈阳性。两组患者的样本在涂片检测中均未出现阴性结果但培养结果为阳性的情况。然而，两名患有衣原体性眼炎的成年患者培养结果为阴性但EB检测呈阳性，他们之前均接受过局部四环素治疗。
