Wang Xiangying, ChangSheng Yang, Yun Liu, Xiaodan Geng
Department of Orthopedic Oncology Surgery, Shandong Cancer Hospital and Institute Affiliated to Shandong First Medical University, Jinan, Shandong, China.
Department of Gastrointestinal Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.
Front Surg. 2025 May 9;12:1447865. doi: 10.3389/fsurg.2025.1447865. eCollection 2025.
Pancreatic cancer is a common malignant tumor that is highly aggressive and can develop distant metastases at an early stage. Pancreatic cancer metastasis often occurs in localized lymph nodes, peritoneum, lungs, and liver. The occurrence of distant soft tissue metastases, especially of skeletal muscles and subcutaneous tissues, is extremely rare. Here, we report a case of pancreatic adenocarcinoma metastatic to the skin of the shoulder.
We have reported here the case of a middle-aged female patient who was admitted to the hospital with a tumor in her right shoulder and a complaint of severe pain for the past 1 month. After completing the relevant examinations, her tumor was entirely surgically resected, and the postoperative pathological result suggested that the pancreatic adenocarcinoma had metastasized. Next, a computed tomography (CT) scan of the chest, abdomen, and pelvis revealed multiple metastases of pancreatic head cancer. Presently, the patient is at an advanced stage of pancreatic cancer and cannot undergo radical surgery. Accordingly, the patient has been referred to the Department of Gastroenterology for comprehensive treatment. We have discussed this rare case in the light of the literature.
Distant soft tissue metastasis of pancreatic cancer is extremely rare and is often detected at an advanced stage, thereby showing a poor prognosis. As this cancer can metastasize very fast and is difficult to resect, specific treatment measures must be taken promptly based on the patient's history, symptoms, and clinical manifestations for a comprehensive treatment.
胰腺癌是一种常见的恶性肿瘤,侵袭性很强,早期即可发生远处转移。胰腺癌转移常发生于局部淋巴结、腹膜、肺和肝脏。远处软组织转移,尤其是骨骼肌和皮下组织转移极为罕见。在此,我们报告一例胰腺腺癌转移至肩部皮肤的病例。
我们在此报告一例中年女性患者,因右肩部肿物伴严重疼痛1个月入院。完成相关检查后,其肿瘤被完整手术切除,术后病理结果提示胰腺腺癌已发生转移。接下来,胸部、腹部和骨盆的计算机断层扫描(CT)显示胰头癌多发转移。目前,该患者处于胰腺癌晚期,无法进行根治性手术。因此,该患者已被转诊至胃肠病科进行综合治疗。我们结合文献对这一罕见病例进行了讨论。
胰腺癌远处软组织转移极为罕见,常于晚期被发现,预后较差。由于这种癌症转移速度非常快且难以切除,必须根据患者病史、症状和临床表现及时采取特定治疗措施进行综合治疗。