金黄色葡萄球菌质粒在枯草芽孢杆菌中的复制与表达。
Replication and expression of plasmids from Staphylococcus aureus in Bacillus subtilis.
作者信息
Ehrlich S D
出版信息
Proc Natl Acad Sci U S A. 1977 Apr;74(4):1680-2. doi: 10.1073/pnas.74.4.1680.
Abstract
One S. aureus plasmid coding for tetracycline resistance, pT127, and four plasmids (pC194, pC221, pC223, and pUB112) coding for chloramphenicol resistance have been introduced by transformation into B, subtilis. The plasmids replicate in--and confer antibiotic resistance upon--their new host. These experiments show that the potential for genetic exchange between diverse bacterial species is greater than has been commonly assumed.
摘要
编码四环素抗性的金黄色葡萄球菌质粒pT127，以及编码氯霉素抗性的四种质粒（pC194、pC221、pC223和pUB112）已通过转化导入枯草芽孢杆菌。这些质粒在其新宿主中复制并赋予抗生素抗性。这些实验表明，不同细菌物种之间进行基因交换的可能性比通常认为的要大。
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