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整合基因见解与人工智能以加强口腔颌面癌护理。

Integrating Genetic Insights and Artificial Intelligence for Enhanced Oral and Maxillofacial Cancer Care.

作者信息

Kadir A K M Shafiul, Asaduzzaman Md, Kundu Joye, Rahman Md Abdur, Rabbany Md Golam, Shemanto Mohammad Ullah, Akhter Rukaiya, Zerin Esrat Jahan, Biswas Amit

机构信息

Quest Bangladesh Biomedical Research Center, Dhaka, Bangladesh.

Rangpur Community Dental College, Rangpur, Bangladesh.

出版信息

Methods Mol Biol. 2025;2952:107-124. doi: 10.1007/978-1-0716-4690-8_7.

Abstract

The integration of artificial intelligence (AI) with genetic insights presents promising avenues for revolutionizing the landscape of oral and maxillofacial cancer (OMC) care. This proposed chapter, titled, aims to explore the synergistic potential of AI and genetic understanding in advancing OMC diagnosis, treatment, and prognosis. The chapter will delve into the genetic changes, including mutations and polymorphisms, contributing to the pathogenesis of oral squamous cell carcinomas (OSCCs) and other malignancies in the oral and maxillofacial region. Additionally, it will elucidate how AI-driven applications, such as computer vision and machine learning, offer novel opportunities for early detection and accurate diagnosis of OMC, thereby improving patient outcomes. By analyzing genetic data and medical records, AI algorithms can identify subtle patterns indicative of OMC development, enabling clinicians to intervene at earlier stages. Moreover, AI facilitates personalized treatment planning by integrating genetic markers with clinical data to tailor therapies based on individual patient profiles, maximizing efficacy and minimizing adverse effects. Furthermore, the chapter will discuss the role of AI in predicting treatment responses and long-term prognoses, aiding clinicians in making informed decisions and improving patient outcomes. Overall, this chapter aims to highlight the transformative potential of integrating genetic insights with AI technologies in OMC care. By leveraging AI-driven approaches for early detection, accurate diagnosis, and personalized treatment, we can significantly enhance patient outcomes and contribute to the broader understanding of AI's role in biomedical research and clinical practice.

摘要

人工智能(AI)与基因见解的整合为彻底改变口腔颌面癌(OMC)护理格局提供了充满希望的途径。这一拟议章节名为,旨在探索AI与基因理解在推进OMC诊断、治疗和预后方面的协同潜力。该章节将深入探讨导致口腔鳞状细胞癌(OSCC)及口腔颌面区域其他恶性肿瘤发病机制的基因变化,包括突变和多态性。此外,它将阐明诸如计算机视觉和机器学习等AI驱动的应用如何为OMC的早期检测和准确诊断提供新机会,从而改善患者预后。通过分析基因数据和医疗记录,AI算法可以识别出表明OMC发展的细微模式,使临床医生能够在更早阶段进行干预。此外,AI通过将基因标记与临床数据相结合,根据个体患者情况定制治疗方案,促进个性化治疗规划,从而最大限度地提高疗效并最小化不良反应。此外,该章节将讨论AI在预测治疗反应和长期预后方面的作用,帮助临床医生做出明智决策并改善患者预后。总体而言,本章旨在强调在OMC护理中整合基因见解与AI技术的变革潜力。通过利用AI驱动的方法进行早期检测、准确诊断和个性化治疗,我们可以显著改善患者预后,并有助于更广泛地理解AI在生物医学研究和临床实践中的作用。

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