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神经质作为抑郁症预后的预测指标。

Neuroticism as a predictor of outcome in depression.

作者信息

Boyce P, Parker G

出版信息

J Nerv Ment Dis. 1985 Nov;173(11):685-8. doi: 10.1097/00005053-198511000-00006.

DOI:10.1097/00005053-198511000-00006
PMID:4056783
Abstract

Low levels of neuroticism have variably been associated with a better outcome of depressive disorders but the interpretation of this phenomenon is clouded by the knowledge that severity of depression may itself confound ratings of neuroticism. To clarify any relationship between neuroticism and outcome, the authors assessed the predictability of neuroticism (as assessed by questionnaire, psychiatrist rating, and subject self-report) in separate groups of psychiatric patients and symptomatic volunteers with nonmelancholic depression. Depressives' judgments of their own neuroticism correlated with neuroticism scores on the Eysenck Personality Inventory (EPI), but neither of these measures predicted improvement at 6 nor 20 weeks. Judgments of neuroticism made by psychiatrists, which did not correlate with EPI neuroticism scores, did predict improvement. The study suggests that differences in defining neuroticism contribute to its variable association with outcome and further suggests the relevance of clinically assessing neuroticism as a personality variable.

摘要

神经质水平较低一直与抑郁症的较好预后存在不同程度的关联,但由于抑郁症的严重程度本身可能会混淆神经质的评分,这一现象的解释变得模糊不清。为了阐明神经质与预后之间的关系,作者在患有非忧郁性抑郁症的精神科患者和有症状志愿者的不同组中,评估了神经质(通过问卷、精神科医生评分和受试者自我报告进行评估)的可预测性。抑郁症患者对自身神经质的判断与艾森克人格问卷(EPI)上的神经质得分相关,但这两种测量方法均未预测出6周或20周时的改善情况。精神科医生对神经质的判断与EPI神经质得分不相关,但确实预测了改善情况。该研究表明,在定义神经质方面的差异导致了其与预后的可变关联,并进一步表明将神经质作为一种人格变量进行临床评估的相关性。

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引用本文的文献

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Stable "trait" variance of temperament as a predictor of the temporal course of depression and social phobia.气质的稳定“特质”变异可预测抑郁和社交恐惧症的病程。
J Abnorm Psychol. 2013 Aug;122(3):611-23. doi: 10.1037/a0032997.
2
Replication and extension: separate personality traits from states to predict depression.复制和扩展:将人格特质与状态分开以预测抑郁。
J Pers Disord. 2014 Apr;28(2):225-46. doi: 10.1521/pedi_2013_27_117. Epub 2013 Jun 20.
3
Neuroticism but not omega-3 fatty acid levels correlate with early responsiveness to escitalopram.
神经质而非ω-3脂肪酸水平与艾司西酞普兰的早期反应相关。
Ann Clin Psychiatry. 2010 Aug;22(3):157-63.
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Shared, not unique, components of personality and psychosocial functioning predict depression severity after acute-phase cognitive therapy.人格和心理社会功能的共同而非独特成分可预测急性期认知治疗后的抑郁严重程度。
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Separate personality traits from states to predict depression.区分人格特质与状态以预测抑郁症。
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