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探索中国结核病患者对人工智能辅助远程健康管理服务的偏好:一项离散选择实验方案

Exploring tuberculosis patients' preferences for AI-assisted remote health management services in China: a protocol for a discrete choice experiment.

作者信息

Wang Xiaojun, Xu Luo, Fu Qian, Lang Dong, Huang Rongping

机构信息

Wuhan Pulmonary Hospital, School of Medicine, Jianghan University, Wuhan, China.

Huazhong University of Science and Technology, School of Medicine and Health Management, Wuhan, China.

出版信息

BMJ Open. 2025 Jul 7;15(7):e101918. doi: 10.1136/bmjopen-2025-101918.

Abstract

INTRODUCTION

Effective health management is critical for patients with tuberculosis (TB), especially given the need for long-term treatment adherence and continuous monitoring. Artificial intelligence (AI)-assisted remote health management services offer a promising solution to increase patient engagement, optimise follow-up and improve treatment outcomes. However, little research has explored TB patients' preferences for these services, and no discrete choice experiment (DCE) has systematically investigated how they make trade-offs between different service attributes. This study aims to (1) identify key attributes of AI-assisted remote health management services that influence TB patients' choices, (2) assess how patients with TB evaluate trade-offs between different service options using a DCE and (3) examine whether preferences vary by sociodemographic characteristics and health system factors.

METHODS AND ANALYSIS

Six attributes were identified through a literature review, focus group discussions and expert consultations. A fractional factorial design was used to generate choice sets while maintaining statistical efficiency and minimising respondent burden. The DCE will be analysed using a multinomial logit model to estimate average preferences. A mixed logit model will be applied to explore preference heterogeneity among participants, incorporating interaction terms with sociodemographic and attitudinal variables. Stratified and latent class analyses will also be considered to further investigate sources of heterogeneity.

ETHICS AND DISSEMINATION

This study complies with the Declaration of Helsinki and has been approved by the Ethics Committee of Wuhan Pulmonary Hospital. All participant data will remain anonymous, and individuals may withdraw from the study at any time. The findings will inform the development of patient-centred AI-assisted TB management strategies and contribute to broader policy discussions on AI integration in TB care. The results will be disseminated through peer-reviewed journal publications, policy briefs, conferences and online platforms.

摘要

引言

有效的健康管理对于结核病患者至关重要,特别是考虑到需要长期坚持治疗和持续监测。人工智能(AI)辅助的远程健康管理服务为提高患者参与度、优化随访并改善治疗效果提供了一个有前景的解决方案。然而,很少有研究探讨结核病患者对这些服务的偏好,并且没有离散选择实验(DCE)系统地研究他们如何在不同服务属性之间进行权衡。本研究旨在:(1)确定影响结核病患者选择的AI辅助远程健康管理服务的关键属性;(2)使用DCE评估结核病患者如何评估不同服务选项之间的权衡;(3)研究偏好是否因社会人口统计学特征和卫生系统因素而异。

方法与分析

通过文献综述、焦点小组讨论和专家咨询确定了六个属性。采用部分因子设计来生成选择集,同时保持统计效率并最小化受访者负担。将使用多项logit模型分析DCE以估计平均偏好。将应用混合logit模型来探索参与者之间的偏好异质性,纳入与社会人口统计学和态度变量的交互项。还将考虑分层分析和潜在类别分析以进一步研究异质性来源。

伦理与传播

本研究符合《赫尔辛基宣言》,并已获得武汉市肺科医院伦理委员会的批准。所有参与者的数据将保持匿名,个人可随时退出研究。研究结果将为以患者为中心的AI辅助结核病管理策略的制定提供信息,并有助于就AI融入结核病护理进行更广泛的政策讨论。结果将通过同行评审的期刊出版物、政策简报、会议和在线平台进行传播。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/811a/12258270/a0f72a597cc8/bmjopen-15-7-g001.jpg

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