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哌甲酯对注意力缺陷障碍男孩同伴互动影响的发育剂量反应分析。

A developmental dose-response analysis of the effects of methylphenidate on the peer interactions of attention deficit disordered boys.

作者信息

Cunningham C E, Siegel L S, Offord D R

出版信息

J Child Psychol Psychiatry. 1985 Nov;26(6):955-71. doi: 10.1111/j.1469-7610.1985.tb00609.x.

DOI:10.1111/j.1469-7610.1985.tb00609.x
PMID:4066819
Abstract

Mixed dyads of 42 normal and 42 ADD boys were videotaped in free play, co-operative task, and simulated classrooms. ADD boys received placebo, 0.15 mg/kg, and 0.50 mg/kg of methylphenidate. ADD boys were more active and off task, watched peers less, and scored lower on mathematics and visual-motor tasks. Older boys interacted less, ignored peer interactions and play more frequently, were less controlling, and more compliant. In class, methylphenidate improved visual motor scores, and reduced the controlling behaviour, activity level, and off task behaviour of ADD boys. Normal peers displayed reciprocal reductions in controlling behaviour, activity level, and off task behaviour.

摘要

对42名正常男孩和42名患有注意力缺陷障碍(ADD)的男孩组成的混合二人组在自由玩耍、合作任务和模拟课堂情境下进行了录像。患有ADD的男孩分别接受了安慰剂、0.15毫克/千克和0.50毫克/千克的哌甲酯。患有ADD的男孩更活跃且注意力不集中,较少观察同伴,在数学和视觉运动任务上得分较低。年龄较大的男孩互动较少,更频繁地忽略同伴互动和玩耍,控制欲较弱且更顺从。在课堂上,哌甲酯提高了患有ADD男孩的视觉运动得分,并减少了他们的控制行为、活动水平和注意力不集中行为。正常同伴在控制行为、活动水平和注意力不集中行为方面也相应减少。

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A developmental dose-response analysis of the effects of methylphenidate on the peer interactions of attention deficit disordered boys.哌甲酯对注意力缺陷障碍男孩同伴互动影响的发育剂量反应分析。
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