生殖因素、口服避孕药与恶性黑色素瘤风险：加拿大西部黑色素瘤研究
Reproductive factors, oral contraceptives and risk of malignant melanoma: Western Canada Melanoma Study.
作者信息
Gallagher R P, Elwood J M, Hill G B, Coldman A J, Threlfall W J, Spinelli J J
出版信息
Br J Cancer. 1985 Dec;52(6):901-7. doi: 10.1038/bjc.1985.275.
Abstract
A study of 361 female melanoma patients and age matched controls was conducted in the four western provinces of Canada. Analysis of reproductive factors showed a significant negative association between number of livebirths and risk of melanoma. The relationship persisted for superficial spreading melanomas after adjustment for host pigmentation factors, freckling, and educational status. An inverse association between bilateral oophorectomy and risk of superficial spreading melanoma was also seen. No association was found between risk of melanoma and age at first birth, age at menarche and age at natural menopause. No association was found between risk of superficial spreading or nodular melanoma and use of either oral contraceptives or menopausal oestrogens.
摘要
在加拿大西部的四个省份对361名女性黑色素瘤患者及年龄匹配的对照组进行了一项研究。生殖因素分析显示，活产数与黑色素瘤风险之间存在显著负相关。在调整宿主色素沉着因素、雀斑和教育程度后，这种关系在浅表扩散性黑色素瘤中依然存在。双侧卵巢切除术与浅表扩散性黑色素瘤风险之间也存在负相关。未发现黑色素瘤风险与初产年龄、月经初潮年龄和自然绝经年龄之间存在关联。未发现浅表扩散性或结节性黑色素瘤风险与口服避孕药或绝经后雌激素的使用之间存在关联。
相似文献
1
Reproductive factors, oral contraceptives and risk of malignant melanoma: Western Canada Melanoma Study.生殖因素、口服避孕药与恶性黑色素瘤风险：加拿大西部黑色素瘤研究
Br J Cancer. 1985 Dec;52(6):901-7. doi: 10.1038/bjc.1985.275.
2
Cutaneous malignant melanoma in women: exogenous sex hormones and reproductive factors.女性皮肤恶性黑色素瘤：外源性性激素与生殖因素
Br J Cancer. 1984 Nov;50(5):673-80. doi: 10.1038/bjc.1984.235.
3
The Danish case-control study of cutaneous malignant melanoma. III. Hormonal and reproductive factors in women.丹麦皮肤恶性黑色素瘤病例对照研究。III. 女性的激素和生殖因素。
Int J Cancer. 1988 Dec 15;42(6):821-4. doi: 10.1002/ijc.2910420603.
4
Reproductive and hormonal factors and breast cancer in a Northern Italian population.意大利北部人群中的生殖与激素因素和乳腺癌
Int J Epidemiol. 1985 Mar;14(1):70-4. doi: 10.1093/ije/14.1.70.
5
Hormonal and reproductive influences and risk of melanoma in women.激素和生殖因素对女性黑色素瘤的影响及风险
Int J Epidemiol. 1998 Oct;27(5):751-7. doi: 10.1093/ije/27.5.751.
6
Cutaneous malignant melanoma in females: the role of hormonal and reproductive factors.女性皮肤恶性黑色素瘤：激素和生殖因素的作用。
Int J Epidemiol. 1990 Sep;19(3):522-6. doi: 10.1093/ije/19.3.522.
7
Hormonal and reproductive factors in melanoma risk.黑色素瘤风险中的激素与生殖因素。
Clin Dermatol. 1992 Jan-Mar;10(1):75-8. doi: 10.1016/0738-081x(92)90060-c.
8
Risk factors for pathologically confirmed benign breast disease.经病理证实的良性乳腺疾病的危险因素。
Am J Epidemiol. 1984 Jul;120(1):115-22. doi: 10.1093/oxfordjournals.aje.a113860.
9
Characteristics that predict risk of breast cancer before and after the menopause.绝经前后乳腺癌风险预测特征。
Am J Epidemiol. 1980 Aug;112(2):258-68. doi: 10.1093/oxfordjournals.aje.a112992.
10
Incidence of thyroid cancer in women in relation to reproductive and hormonal factors.女性甲状腺癌发病率与生殖及激素因素的关系。
Am J Epidemiol. 1984 Sep;120(3):423-35. doi: 10.1093/oxfordjournals.aje.a113907.
引用本文的文献
1
Exogenous Hormone Factors in Relation to the Risk of Malignant Melanoma in Women: A Systematic Review and Meta-Analysis.外源性激素因素与女性恶性黑色素瘤风险的关系：一项系统评价和荟萃分析
Cancers (Basel). 2022 Jun 29;14(13):3192. doi: 10.3390/cancers14133192.
2
Association of the Age at Menarche with Site-Specific Cancer Risks in Pooled Data from Nine Cohorts.初潮年龄与九个队列汇总数据中特定部位癌症风险的关联。
Cancer Res. 2021 Apr 15;81(8):2246-2255. doi: 10.1158/0008-5472.CAN-19-3093. Epub 2021 Apr 5.
3
Estrogen Receptors and Melanoma: A Review.雌激素受体与黑色素瘤：综述。
Cells. 2019 Nov 19;8(11):1463. doi: 10.3390/cells8111463.
4
Ethinylestradiol and Levonorgestrel as Active Agents in Normal Skin, and Pathological Conditions Induced by UVB Exposure: In Vitro and In Ovo Assessments.炔雌醇和左炔诺孕酮作为正常皮肤和 UVB 照射诱导的病理条件下的活性药物：体外和体内评估。
Int J Mol Sci. 2018 Nov 14;19(11):3600. doi: 10.3390/ijms19113600.
5
Alcohol consumption and risk of melanoma among women: pooled analysis of eight case-control studies.女性饮酒与黑色素瘤风险：八项病例对照研究的汇总分析
Arch Dermatol Res. 2015 Nov;307(9):819-28. doi: 10.1007/s00403-015-1591-x. Epub 2015 Jul 16.
6
Age at first birth and melanoma risk: a meta-analysis.初产年龄与黑色素瘤风险：一项荟萃分析。
Int J Clin Exp Med. 2014 Dec 15;7(12):5201-9. eCollection 2014.
7
Progesterone and estrogen receptors in conjunctival melanoma and nevi.结膜黑色素瘤和痣中的孕激素和雌激素受体。
Graefes Arch Clin Exp Ophthalmol. 2014 Feb;252(2):359-65. doi: 10.1007/s00417-013-2523-0. Epub 2013 Nov 26.
8
Menopausal hormone therapy and risks of melanoma and nonmelanoma skin cancers: women's health initiative randomized trials.绝经激素治疗与黑色素瘤和非黑色素瘤皮肤癌的风险：妇女健康倡议随机试验。
J Natl Cancer Inst. 2011 Oct 5;103(19):1469-75. doi: 10.1093/jnci/djr333. Epub 2011 Aug 30.
9
Biologic markers of sun exposure and melanoma risk in women: pooled case-control analysis.女性日光暴露和黑素瘤风险的生物标志物：汇总病例对照分析。
Int J Cancer. 2011 Aug 1;129(3):713-23. doi: 10.1002/ijc.25691. Epub 2010 Nov 16.
10
A pooled analysis of 10 case-control studies of melanoma and oral contraceptive use.一项关于黑色素瘤与口服避孕药使用情况的10项病例对照研究的汇总分析。
Br J Cancer. 2002 Apr 8;86(7):1085-92. doi: 10.1038/sj.bjc.6600196.
本文引用的文献
1
Malignant melanoma associated with breast cancer.与乳腺癌相关的恶性黑色素瘤。
South Med J. 1980 Nov;73(11):1493-7. doi: 10.1097/00007611-198011000-00023.
2
Estrogen receptors in patients with malignant melanoma.恶性黑色素瘤患者中的雌激素受体
Cancer. 1980 Oct 15;46(8):1785-6. doi: 10.1002/1097-0142(19801015)46:8<1785::aid-cncr2820460815>3.0.co;2-0.
3
A study of cancer, parity and age at first pregnancy.一项关于癌症、生育次数及首次怀孕年龄的研究。
J Chronic Dis. 1980;33(10):595-605. doi: 10.1016/0021-9681(80)90002-8.
4
An epidemiologic study of epithelial carcinoma of the ovary.卵巢上皮癌的一项流行病学研究。
Am J Epidemiol. 1981 Sep;114(3):398-405. doi: 10.1093/oxfordjournals.aje.a113207.
5
A case-control study of the possible association between oral contraceptives and malignant melanoma.一项关于口服避孕药与恶性黑色素瘤之间可能关联的病例对照研究。
Br J Cancer. 1981 Jul;44(1):45-50. doi: 10.1038/bjc.1981.145.
6
Changing patterns of breast cancer among American women.美国女性乳腺癌模式的变化。
Am J Public Health. 1980 Aug;70(8):832-5. doi: 10.2105/ajph.70.8.832.
7
A case-control study of cancer of the endometrium.一项子宫内膜癌的病例对照研究。
Am J Epidemiol. 1982 Aug;116(2):333-42. doi: 10.1093/oxfordjournals.aje.a113417.
8
Oral contraceptive use and malignant melanoma.口服避孕药的使用与恶性黑色素瘤
J Natl Cancer Inst. 1982 Apr;68(4):537-9.
9
Exogenous estrogens and other factors in the epidemiology of breast cancer.外源性雌激素及乳腺癌流行病学中的其他因素。
J Natl Cancer Inst. 1981 Aug;67(2):327-33.
10
Lack of an elevated risk of malignant melanoma in relation to oral contraceptive use.口服避孕药使用与恶性黑色素瘤风险升高无关。
J Natl Cancer Inst. 1984 Mar;72(3):617-20.
Zotero 插件