van Wachem P B, Beugeling T, Feijen J, Bantjes A, Detmers J P, van Aken W G
Biomaterials. 1985 Nov;6(6):403-8. doi: 10.1016/0142-9612(85)90101-2.
The in vitro interaction of human endothelial cells (HEC) and polymers with different wettabilities in culture medium containing serum was investigated. Optimal adhesion of HEC generally occurred onto moderately wettable polymers. Within a series of cellulose type of polymers the cell adhesion increased with increasing contact angle of the polymer surfaces. Proliferation of HEC occurred when adhesion was followed by progressive flattening of the cells. Our results suggest that moderately wettable polymers exhibit a serum and/or cellular protein adsorption pattern that is favourable for growth of HEC.
研究了人内皮细胞（HEC）与不同润湿性聚合物在含血清培养基中的体外相互作用。HEC的最佳黏附通常发生在中等润湿性聚合物上。在一系列纤维素类聚合物中，细胞黏附随着聚合物表面接触角的增加而增加。当细胞黏附后逐渐变平时，HEC发生增殖。我们的结果表明，中等润湿性聚合物表现出有利于HEC生长的血清和/或细胞蛋白吸附模式。
