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酗酒者的后代具有增强的对抗性安慰剂反应。

Offspring of alcoholics have enhanced antagonistic placebo response.

作者信息

Newlin D B

出版信息

J Stud Alcohol. 1985 Nov;46(6):490-4. doi: 10.15288/jsa.1985.46.490.

DOI:10.15288/jsa.1985.46.490
PMID:4087912
Abstract

In this study, 85 college-age men who reported normal drinking practices believed they were drinking malt liquor when they actually drank dealcoholized beer. Following drinking, 11 subjects with an alcoholic biological father showed a significantly larger heart rate decrease (p less than .05) than subjects with a nonalcoholic father. The results are discussed in terms of opponent process and classical conditioning theories of addiction, and the etiological pathway from risk factor to final manifestation of alcoholism.

摘要

在本研究中,85名报告有正常饮酒习惯的大学适龄男性认为自己喝的是麦芽酒,而实际上他们喝的是脱醇啤酒。饮酒后,11名有酗酒生物学父亲的受试者心率下降幅度显著大于(p小于0.05)有非酗酒父亲的受试者。本文根据成瘾的对抗过程和经典条件反射理论,以及从危险因素到酒精中毒最终表现的病因途径对结果进行了讨论。

相似文献

1
Offspring of alcoholics have enhanced antagonistic placebo response.酗酒者的后代具有增强的对抗性安慰剂反应。
J Stud Alcohol. 1985 Nov;46(6):490-4. doi: 10.15288/jsa.1985.46.490.
2
Placebo responding in the same direction as alcohol in women.女性中安慰剂反应与酒精反应方向相同。
Alcohol Clin Exp Res. 1989 Feb;13(1):36-9. doi: 10.1111/j.1530-0277.1989.tb00280.x.
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Subjective responses to alcohol in sons of alcoholics and control subjects.酗酒者之子与对照受试者对酒精的主观反应。
Arch Gen Psychiatry. 1984 Sep;41(9):879-84. doi: 10.1001/archpsyc.1984.01790200061008.
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Compensatory responses to placebo vary with presumed personality "risk" for alcoholism and drinking habits.对安慰剂的代偿反应因假定的酒精成瘾人格“风险”和饮酒习惯而异。
Int J Addict. 1994 Apr;29(5):583-91. doi: 10.3109/10826089409047401.
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Behavioral and EEG responses to alcohol in nonalcoholic men with a family history of alcoholism.有酗酒家族史的非酗酒男性对酒精的行为和脑电图反应。
Prog Neuropsychopharmacol Biol Psychiatry. 1988;12(6):873-85. doi: 10.1016/0278-5846(88)90083-8.
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Effect of naltrexone on alcohol "high" in alcoholics.纳曲酮对酗酒者酒精“快感”的影响。
Am J Psychiatry. 1995 Apr;152(4):613-5. doi: 10.1176/ajp.152.4.613.
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The antagonistic placebo response to alcohol cues.对酒精线索的对抗性安慰剂反应。
Alcohol Clin Exp Res. 1985 Sep-Oct;9(5):411-6. doi: 10.1111/j.1530-0277.1985.tb05573.x.
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Aggressiveness, family history of alcoholism, and the heart rate response to alcohol intoxication.攻击性、酗酒家族史以及对酒精中毒的心率反应。
Exp Clin Psychopharmacol. 2003 May;11(2):158-66. doi: 10.1037/1064-1297.11.2.158.
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Alcohol expectancy and conditioning in sons of alcoholics.酗酒者儿子的酒精期望与条件作用
Adv Alcohol Subst Abuse. 1987 Summer;6(4):33-57. doi: 10.1300/J251v06n04_04.
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Experience of a "slip" among alcoholics treated with naltrexone or placebo.接受纳曲酮或安慰剂治疗的酗酒者中出现“滑倒”的经历。
Am J Psychiatry. 1996 Feb;153(2):281-3. doi: 10.1176/ajp.153.2.281.

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