可使阿米卡星磷酸化的具有广泛底物范围的质粒介导的氨基糖苷磷酸转移酶。
Plasmid-medicated aminoglycoside phosphotransferase of broad substrate range that phosphorylates amikacin.
作者信息
Courvalin P, Davies J
出版信息
Antimicrob Agents Chemother. 1977 Apr;11(4):619-24. doi: 10.1128/AAC.11.4.619.
Abstract
A plasmid-mediated aminoglycoside phosphotransferase that phosphorylates amikacin has been detected in clinical isolates of Staphylococcus aureus. This enzyme does not confer detectable amikacin resistance to the strains.
摘要
在金黄色葡萄球菌的临床分离株中检测到一种可使阿米卡星磷酸化的质粒介导的氨基糖苷磷酸转移酶。该酶并未使这些菌株产生可检测到的对阿米卡星的耐药性。
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