Salvin S B, Nishio J, Shonnard J T
Infect Immun. 1974 Apr;9(4):631-5. doi: 10.1128/iai.9.4.631-635.1974.
In addition to the activities associated with migration inhibitory factor and type II interferon, two other inhibitory activities have been found in the sera of mice infected intravenously with BCG and 3 weeks later challenged intravenously with old tuberculin. Growth of three bacteria, Streptococcus faecalis, Staphylococcus aureus, Pseudomonas aeruginosa, and one yeast, Candida albicans, was inhibited in vitro by a factor or factors in the serum. Also, hematopoiesis of mouse bone marrow cells in a soft agar medium was suppressed by the serum.
除了与迁移抑制因子和II型干扰素相关的活性外,在静脉注射卡介苗并于3周后静脉注射旧结核菌素进行攻击的小鼠血清中还发现了另外两种抑制活性。血清中的一种或多种因子在体外抑制了三种细菌(粪肠球菌、金黄色葡萄球菌、铜绿假单胞菌)和一种酵母(白色念珠菌)的生长。此外,血清还抑制了软琼脂培养基中小鼠骨髓细胞的造血作用。