Wood H N, Braun A C, Brandes H, Kende H
Proc Natl Acad Sci U S A. 1969 Feb;62(2):349-56. doi: 10.1073/pnas.62.2.349.
One member of a new class of cell division-promoting substances, which are nicotinamide derivatives, has been found to be present in dividing cells of tobacco and cactus. These plants are taxonomically far removed from one another and from Vinca rosea L., the plant species from which the new substances were first isolated. Because of their apparent wide distribution among dicotyledonous plant species, the question is raised as to whether the nicotinamide derivatives rather than the purine cytokinins may not, in fact, be the naturally occurring cell division factors that are directly involved in promoting cytokinesis in higher plant species. Unequivocal evidence is presented to show that the nicotinamide derivatives do not owe their biological activity to contamination by 6-substituted purine cytokinins.
一类促进细胞分裂的新物质是烟酰胺衍生物，已发现其中一种存在于烟草和仙人掌的分裂细胞中。从分类学角度来看，这些植物彼此之间以及与长春花（新物质最初从中分离出来的植物物种）都相距甚远。由于它们明显广泛分布于双子叶植物物种中，因此引发了一个问题：实际上，烟酰胺衍生物而非嘌呤细胞分裂素，是否可能是直接参与促进高等植物物种细胞分裂的天然存在的细胞分裂因子。文中提供了明确的证据表明，烟酰胺衍生物的生物活性并非归因于6-取代嘌呤细胞分裂素的污染。
